Flashcards
SDE 1
Flashcards do conjunto (13)
- 1Therapeutic range for Carbamazepine:4-12 mcg/mL
- 2Therapeutic range for Phenytoin:Total = 10-20 mcg/mL; Free = 1-2 mcg/mL
- 3Therapeutic range for Phenobarbital:10-40 mcg/mL
- 4Therapeutic range for Valproic acid:50-100 mcg/mL
- 5Long term adverse effects ketogenic diet1. kidney stones.
2. increased bone fractures.
3. slowed growth or weight gain.
4. constipation.
5. dehydration.
6. hypercholesterolemia. - 6Adverse effects of VNS1. hoarseness
2. cough
3. nausea
4. occasional neck pain, or
5. a tingling sensation during stimulation - 7Serious adverse effects of VNS1. infection at the operative site or low-grade fever
2. paralysis of the vagal nerve, left face, or left vocal cord; and
3. urinary retention. - 8AEDS that require renal adjustments [Hint] FEGFBM
EZG
GBP - 9AEDS that require renal adjustments [Hint] LLBPAEDS that require renal adjustments
[Hint]
LCM
LEV
BRV
PER - 10AEDS that require renal adjustments [Hint] PTZPBG
TPM
ZNS - 11Drugs w/ CYP 450 metabolism HINT: VP-COPPVPA
PER
CBZ
OXC
PHB & PHT - 12Factors that favor successful withdrawal of AED therapy1. Patients who are seizure-free for 2 to 4 years
2. Patients who achieve complete seizure control within 1 year of onset.
3. whose seizure onset >2 years old and <35 years old; and
4. Patients that have a normal EEG and neurologic examination. - 13Poor prognostic indicators that may warrant lifelong therapy1. high seizure frequency
2. repeated status epilepticus episodes
3. a combination of seizure types
4. development of abnormal mental functioning