Pharmacology- Antimicrobial Drugs- Sulfonamides and Quinolones- 4th Year- PMU

Sulfadiazine

Sulfacetamide

Sulfisoxazole

Co-trimoxazole

Co-trimoxazole

Sulfacetamide

Sulfaguanidine

Sulfisoxazole

they are synthetic analogues of p-aminobenzoic acid (PABA) and complete with it for the enzyme dihydropteroate synthetase

they increase the permeability of the bacterial cell membrane

they inhibit bacterial wall synthesis

they inhibit the synthesis of bacterial dihydrofolic acid

have broad antibacteriai spectrum

have narrow antibacterial spectrum

they are bactericidal

they are bacteriostatic

contains trimethoprim and sulfamethoxazole

contains sulfadoxine and pyrimethamine

has bactericidal effect

is taken every 12 hours

is used as an antimalarial drug

is combined drug containing long-acting sulfonamide

mains sulfadoxine and pyrimethamine

contains trimethoprim and sulfamethoxazole

bacteriostatic drugs

bactericidal drugs

antiviral drugs

narrow spectrum antimicrobial drugs

administration of folic acid

adequate hydration

alkalinization of urine

acidification of urine

hemapoietic disturbances

heart failure

hypersensitivity

crystalluria

renal or liver impairment

pregnancy and breast-feeding

new-borns and infants less than 2 months of age

arterial hypertension

petentiation of the effect of oral anticoagulants (warfarin)

antagonism when applied together with penicillines

synergism when applied together with penicillines

potentiation of the hypoglycaemic effect of oral antidiabetic