Quiz
Adrenegic Drugs- Pharmacology 4th Year- PMU
Questions in this quiz (31)
1According to their mechanism of action the adrenergic agonists can be divided in:
- Adirect agonists
- Bindirect agonists
- Cagonists with mixed mechanism of action
- Dnatural compounds
2α1-adrenoceptors are located on:
- Apresynaptic neuronal endings
- Bpostsynaptic neuronal endings
- Cblood vessels
- Diris dilator muscle
3β1-adrenoceptors are located on:
- Apostsynaptic neuronal endings
- Bpresynaptic neuronal endings
- Cmyocardial cells
- Djuxtaglomerular apparatus in the kidney
4β2-adrenoceptors are located on:
- Apostsynaptic neuronal endings
- Bbronchial smooth muscles
- Cliver
- Duterus (womb)
5β3-adrenoceptors are located in:
- Aadipose tissue
- Burinary bladder
- Cpresynaptic neuronal endings
- Dbronchial smooth muscles
6Pharmacological effects of Epinephrine are:
- Apositive chronotropic effect
- Bblood pressure elevation
- Cbronchial smooth muscles dilation
- Delevated levels of blood sugar
7Indications for the clinical use of Epinephrine are:
- Aanaphylactic shock
- Bhypoglycaemia
- Carrhythmia
- Dglaucoma with wide iridocorneal angle
8Potential adverse drug reactions of Epinephrine are:
- Ahypoglycaemia
- Barrhythmia
- Ctremor
- Danxiety and restlessness
9Clinical indications for prescribing α1-agonists are:
- Aarterial hypotension
- Bacute rhinitis
- Casthma attack
- Dheart block
10Pharmacological effects of the selective β2-agonists are:
- Apupillary dilation
- Bbronchial dilation
- Cblood pressure elevation
- Drelaxation of uterine muscle
11Which of the following drugs are selective β2-agonists?
- Alsoprenalini sulfas
- BOrciprenalini sulfas
- CSalbutamol
- DSalmeterol
12β2-agonists are indicated in:
- Abronchial asthma
- Bdigitalis intoxication
- Carterial hypertension
- Dthreatening abortion
13Adverse drug reactions of β2-agonists are:
- Afinger tremor
- Bbronchial dilatation
- Chyperglycemia
- Dtolerance
14What are the main features of the indirect-acting adrenergic agonists?
- Astimulation of central nervous system
- Bdrug tolerance and dependence
- Chave no effect on the cardio-vascular system
- Dused for treatment of narcolepsy and attention deficiency hyperactivity disorder (ADHD)
15Clinically desirable interactions can occur between β2-agonists and:(find correct answer)
- Atricyclic antidepressants
- Binhaled corticosteroids
- Cinhaled antimuscarinic drugs
- Dbeta blockers
16Mechanisms of action of the presynaptic adrenolytics are:
- Ablockade of the presynaptic α2-receptors
- Bactivation of the presynaptic α2-receptors
- Cconversion to a “false“ neurotransmitter
- Dblockade of the phosphodiesterase enzyme
17Which of the following drugs act as agonists of the presynaptic α2-adrenoceptors?
- ASalbutamol
- BClonidini hydrochloridum
- Cα-Methyldopum (Dopegyt)
- DSotalol
18Pharmacological effects of Clonidin are:
- Adecreased peripheral vascular resistance
- Bantihypertensive
- Cinhibition of gastric secretion
- Dantiarrhythmic
19Adverse drug reactions of Clonidin are:
- ADry mouth
- BDrowsiness and depression
- CHypertensive attacks following abrupt cessation of treatment
- DCNS stimulation
20For Methyldopa is true:
- Ahas antihypertensive effect
- Bit is safe in pregnancy
- Ccould cause drug-induced parkinsonism
- Dused to treat threatening abortion
21Which of the following drugs are α1-adrenoblockers?
- APrazosin
- BDoxazosin
- CClonidin
- DChlorpromazin
22Pharmacological effects of Prazosin are:
- Adilation of the resistive and capacitive vessels
- Bantihypertensive
- Crelaxation of the muscles in the prostate and bladder neck
- Dhyperglycaemia
23Adverse drug reactions of α1-adrenoblockers are:
- Aorthostatic collapse
- Bhypokalemia
- Cfluid retention
- Dhypoglycaemia
24Which of the following drugs are non-selective β-blockers?
- AAtenolol
- BPindolol
- CAcebutolol
- DPropranolol
25Which of the following drugs are selective β1-blockers?
- AAtenolol
- BPindolol
- CPropranolol
- DMetoprolol
26β-blockers are indicated in case of:
- Ahypertension
- Bbronchial asthma
- Carrhythmia
- Dischaemic heart disease
27Pharmacological effects of B-blockers are:
- Abronchodilation
- Bnegative inotropic effect
- Cpositive chronotropic effect
- Dnegative chronotropic effect
28β-blocker approved for topical use in treatment of glaucoma is:
- ABisoprolol
- BMetoprolol
- CTimolol
- DPropranolol
29When applied topically in the eye the B-blocker Timolol will:
- Aincrease the intraocular pressure
- Bdecrease the intraocular pressure
- Ccause miosis
- Dcause mydriasis
30Potential adverse drug reactions of β-blockers are.
- Ahypoglycaemia
- Bbronchoconstriction
- Chyperglycaemia
- Dnightmares
31For long-term treatment with β-blockers is true:
- Aup-regulation of B-adrenergic receptors
- Bdown-regulation of B-adrenergic receptors
- Cthe therapy should be ceased abruptly
- Dthe therapy should not be ceased abruptly
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- Adrenegic Drugs- Pharmacology 4th Year- PMU
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