Cornea - Chapter 3

Herpes Simplex Conjunctivitis

Chlamydial Conjunctivitis

Molluscum Contangiosum conjunctivitis

Brimonidine Conjunctivitis

Ocular Rosacea

Stevens-Johnson Syndrome

Chemical Injury

Mucus Membrane Pemphigoid

Sarcoidosis

Sarcoidosis

Stevens-Johnson Syndrome

Cat Scratch Disease

Foreign body reaction

Anesthetic Abuse

Viral Keratitis

Reactive arthritis

Syphilis

Tuberculosis

Benign lymphoid folliculosis is clusters of enlarged, noninflamed follicles occasionally seen in the forniceal or inferior palpebral conjunctiva of children and adolescents.

Papillae are sprout spokelike capillaries that become surrounded by edema and mixed inflammatory infiltrate, producing raised elevations under the conjunctival epithelium.

Keratic precipitates are clumps of inflammatory cells that adhere to the back of the cornea and come from the anterior uvea during the course of keratitis or uveitis.

Appearance of keratic precipitates depends on the cell composition; for example neutrophils and lymphocytes give the large clumps of "mutton fat" appearance

Disorders of lid aperture

Contact lens wear

Vitamin A Deficiency

Sjogren Disease

Low blink rate

Sjogren syndrome is a T cell mediated disease leading to destruction of lacrimal gland.

Primary Sjogren syndrome is a well defined connective tissue disorder or immune dysfunction.

Involvement of salivary glands is common in Sjogren syndrome.

Rheumatoid arthritis is the most common underlying disorder associated with secondary Sjogren syndrome.

It is more common in Asian ethnicity than Caucasians.

Hypersecretory MGD can be cicatricial or noncicatricial.

Tear break up time is often increased in MGD.

Telangiectatic blood vessels often courses from anterior to posterior lid margin in MGD.

Trachoma and mucous membrane pemphigoid are examples of noncicatricial MGD.

Smoking cessation

Punctal occlusion

Humidifier and or moisture shield glasses

Topical cyclosporine A 0.05%

Tear duct Probing

Lifitegrast 5% (Xiidra)

Scleral contact lenses

Omega-3 fatty acids

Collagen plugs are a form of permanent punctal occlusion.

Silicone plugs last months to years.

Permanent punctal occlusion has a risk of infectious canaliculitis.

Polydioxanone provide about 6 months of punctal occlusion.