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Defects of development in face, palate, lip, and pharynx (CF 7-8)

Liz Maas 12 questions

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Questions in this quiz (12)

  1. 122q11 is a microdeletion syndrome which includes DiGeorge syndrome and Velocardiofacial syndrome. DiGeorge involves craniofacial malformation, Velocardiofacial involves deficiency of pharyngeal glands, and both involve cardiovascular abnormalities
    1. ABoth true
    2. BFirst true, second false
    3. CFirst false, second true
    4. DBoth false
  2. 2Which of the following is correct?
    1. AImpaired development of the first and second pharyngeal arches can cause micrognathia, high palate, low set ears, and middle ear issues
    2. BDefects of the fourth pharyngeal arch artery can cause disruption of development in the cardiac septum
    3. CDefects of the third pharyngeal pouch can cause hypocalcemia, impaired T cell functions, or missing t-cells
    4. DPA and PAA
    5. EPA and PP
  3. 3Mandibulofacial dysostosis is caused by a mutation in TCOF1 which encodes a protein called Treacle. Because it is expressed in the neuroepithelium, its absence leads to increased cell death and decreased proliferation.
    1. ABoth true
    2. BFirst true, second false
    3. CFirst false, second true
    4. DBoth false
  4. 4Which of the following is correct?
    1. ATreacher Collins is a mutation or deletion disorder with affected structures mostly being from the first pharyngeal arch
    2. BPierre Robin Sequence/Syndrome involves the mostly the first pharyngeal arch and manifests as micrognathia, glossoptosis, and cleft secondary palate
    3. CGoldenhar syndrome involves abnormal development of only the first pharyngeal arch and usually affects only one side
    4. DPR/TC
    5. EPR/TC/GS
  5. 5Branchial fistulas occur when the second pharyngeal arch fails to grow caudally over the 3rd and 4th pharyngeal arches. The resultant cysts are often found directly posterior to the sternocleidomastoid muscle
    1. ABoth true
    2. BFirst true, second false
    3. CFirst false, second true
    4. DBoth false
  6. 6Which of the following is correct?
    1. AThe alae, tip and bridge of the nose, philtrum, and medial upper lip come from the medial nasal prominence
    2. BThe lower lip, chin, and lower jaw come from the mandibular prominence
    3. CThe lateral portion of the upper lip, cheeks, and incisors are derived from the maxillary prominence
    4. Dmandibular and maxillary prominence
    5. Eall of the choices
  7. 7Development of the secondary palate occurs after the primary palate via fusion of the palatal shelves. The shelves vertically elongate downwards on either side of the tongue.
    1. ABoth true
    2. BFirst true, second false
    3. CFirst false, second true
    4. DBoth false
  8. 8Which is the correct order of secondary plate development?
    1. Aformation, fusion, elongation, elevation, horizontal growth
    2. Bformation, elongation, elevation, horizontal growth, fusion
    3. Cformation, horizontal growth, elongation, elevation, fusion
    4. Dformation, elongation, horizontal growth, elevation, fusion
  9. 9Cells of the medial epithelial seam undergo apoptosis as they are displaced and extruded prior to ossification of the palate. Ossification only occurs at the primary palate
    1. ABoth true
    2. BFirst true, second false
    3. CFirst false, second true
    4. DBoth false
  10. 10Cleft primary palate always comes with cleft lip because of a lack of fusion between the lateral nasal and maxillary prominences. Oblique facial clefts occur due to lack of fusion between maxillary prominence and medial nasal prominences
    1. ABoth true
    2. BFirst true, second false
    3. CFirst false, second true
    4. DBoth false

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Author
Liz Maas
Language
English
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