Question 1
Question
During Meiosis I, chromosome structure changes only slightly
Question 2
Question
Which stage of chromosome momvement is this?
Answer
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Leptotene
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Xygotene
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Diplotene
Question 3
Question
Name this type of chromosome arrangement
Answer
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Leptotene
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Zygotene
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Pacytene
Question 4
Question
What is this stage called?
Answer
-
Leptotene
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Pacytene
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Diplotene
Question 5
Answer
-
Diplotene
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Pacytene
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Leptotene
Question 6
Question
In which stage of chromosome rearrangement are Rabl and Bouquet formations found?
Answer
-
Zygotene
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Diplotene
-
Pacytene
Question 7
Question
Chromosome movement is vital for pairing
Question 8
Question
Match the word to it's definition- the occurrence of linked genes in non random proportions in members of the population
Question 9
Question
Linkage between two genes can only be broken by _
Answer
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Crossing over
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Rabl formations
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Linkage disequilibrium
Question 10
Question
Genetic Map Distance = % crossing over
Question 11
Question
Genetic Map distance is measured in
Answer
-
centiMorgans (cM)
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centiMullers (cM)
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centiMorays (cM)
Question 12
Answer
-
1% crossover recombination
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10% crossover recombination
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5% crossover recombination
Question 13
Question
% Crossing over = [(No of recombinants/total gametes) x 100] x 2
Question 14
Question
How is meiotic recombination initiated?
Answer
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Double strand breaks
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Single strand breaks
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T-T lesions
Question 15
Question
Which of the following proteins non-randomly damages the DNA in meiotic cells?
Question 16
Question
Once breaks are formed by Spo_, they are monitored by mismatch repair proteins
Question 17
Question
What is the role of mismatch repair proteins?
Answer
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To monitor induced DNA damage
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To detect and reverse any incorrect DNA pairings
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To detect and amplify any incorrect pairings
Question 18
Question
The damage to the DNA is done one chromosome at a time
Question 19
Question
Why are the breaks formed useful?
Answer
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They ensure meiotic cell machinery is working properly
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They are a precursor to chiasma
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They prevent meiosis until the cell is ready
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Ensure the pairing of homologous chromosomes
Question 20
Question
Meiosis can proceed happily without the DNA damage occuring
Question 21
Question
All chromosomes will get at least once crossover (known as interference)
Question 22
Question
What is the synaptonemal complex?
Question 23
Question
Which of the following are meiosis specific repair proteins?
Answer
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Spo11
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EXO1
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MLH1
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MLH3
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Braf
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C-myc
Question 24
Question
Increasing the distance between two genes decreases the chance of a crossover occurring between them
Question 25
Question
Parent Genotypes are homologous for AB & ab respectively
The gametes have the genotypes 35, 15, 15, 35 for AB, Ab, aB and ab respectively
How far apart are AB/ab in cM?