Physiology Defintions Year 2 Test 2

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Physiology
Hubey Ak
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Haematocrit (HCT) Reference Value: Female 4.0 - 5.4 .10(12).L-1 Male 4.6 - 6.2 .10(12).L-1
pH of arterial blood 7.45
pH of venous blood 7.35
Definition: Normovolemia Normal Blood Volume
Definition:Hypervolemia Abnormally increased volume of blood
Definition: Hypovolemia Abnormally decreased volume of blood
Definition: Normocythaemia Normal condition of the RBC
Definition: Oligocythaemia A reduction in the RBC
Definition: Policythaemia Abnormal increase in RBC
Definition: Acidosis Pathological condition characterized by an Increase in hydrogen ion concentration (Decrease in pH)
Definition: Alcalosis Pathological condition characterized by an Decrease in hydrogen ion concentration (Increase in pH)
Definition: Hypoproteinoemia Deficiency of protein in the blood.
Rules of blood transfusion: 1. 2. 3. Determination of the blood types of Donor and Recipient with test sera Direct Cross matching: 1st Stage: Serum of R + blood of D >No Agl 2nd Stage: Serum D + Blood R > No Agl Biological Testing - Monitor occurrence of symptoms.
Symptoms of adverse Transfusion reaction: Chills, Headache, Shivering, Jaundice, Waist pain
Composition of Whole Blood: 55% Plasma 45% Cells
Composition of Blood Plasma 10% Dry Residue Solids 90% Water
Composition of the 10% Dried Plasma Residue 0.9% Salts 1.5% Organic Sub Fibrogen 2.7% Globulins 4.5% Albumins
Blood transfusion of a different but compatible group may be performed as; How much Whole Blood? up to 500ml of Whole Blood
Blood transfusion of a different but compatible group may be performed as; How much RBC (Include ratio titer) Up to 1000 ml of RBC; When the titer of the different agglutinins is below 1:16 (at this dilution the incompatible antibodies do not agglutinate the RBC of the recipient).
Fundamental principle of blood transfusion: Recipient's plasma does not agglutinate donor's RBC.
How much plasma can we transfuse if the Hemacrit is 0.4 - 0.5 (50%) - 250ml
Hemacrit Defintion Ratio of volume electrolyte mass to volume of whole blood.
Physiological Components of Haem Oxyhaemaglobin Carbonin/Haemglobin
RBC Reference Value 4 to 5.2 . 10(12) . L-1
Heme group O2
Globin Group CO2
Hemoglobin Reference Value Female: 120 - 160 g.L-1 Male: 140 - 180 g.L-1
Erythrocyte Reference Value Female: 4.0 - 5.4 .10(12).L-1 Male: 4.6 - 6.2 .10(12).L-1
Define Erythrocytosis Refers to a documented increase of red cell mass
Define Electropenia Decrease in RBC
Anemia Electropenia And/Or Hypoglobnia
Define Differential Blood Count The blood differential test measures the percentage of each type of white blood cell (WBC) that you have in your blood.
Reference Value - Leucocytes 3.50 - 10.50 .10(9). L-1
Reference Value - Platelets (Thrombocytes) 140 - 400 .10(9).L-1
Define Leucocytosis An increase in the number of white cells in the blood
Define Leucopenia A Decrease in the number of white cells in the blood
Define Lymphocytosis Lymphocytosis is an increase in the number or proportion of lymphocytes in the blood. In absolute lymphocytosis, the total lymphocyte count is elevated.
Define Lymphopenia Lymphocytopenia, or lymphopenia, is the condition of having an abnormally low level of lymphocytes in the blood.
Define Monocytosis Monocytosis is an increase in the number of monocytes circulating in the blood. Monocytes are white blood cells that give rise to macrophages and dendritic cells in the immune system.
Define Eosinophilia an increase in the number of eosinophils in the blood, occurring in response to some allergens, drugs, and parasites, and in some types of leukaemia.
Define Thrombocytosis Presence of high platelet counts in the blood
Define Thrombocytopenia deficiency of platelets in the blood. This causes bleeding into the tissues, bruising, and slow blood clotting after injury.
Define Immunity Ability of an organisim to recognize and destroy genetic material
Difference between Segmented and Banded Neutrophils Shape of the nucleus (Segmented into 3 or 4 parts or Banded into one long "stabs")
When does Eosinophillia occur? Allergic reactions + some Parasitic Diseases
Define and Explain Glucocorticoids Any of a group of corticosteroids (e.g. hydrocortisone) which are involved in the metabolism of carbohydrates, proteins, and fats and have anti-inflammatory activity. Decease the Eosinophilic Number
Define Haemostasis Haemostasis is the human body's response to blood vessel injury and bleeding. It involves a coordinated effort between platelets and numerous blood clotting proteins (or factors), resulting in the formation of a blood clot and subsequent stopping of the bleed.
Define Afibrinogenemia Congenital afibrinogenemia is a rare, genetically inherited blood disorder in which the blood does not clot normally due to the lack of fibrinogen, a blood protein necessary for coagulation
Define Haemophilia Haemophilia is an inherited condition that affects the blood's ability to clot.
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