Course
Medchem
opoids
Modules (4)
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morphine levo class : phenanthrene
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beznoquinone (metabolite of morphine) toxic less active than morphine
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3-deoxymorphine lower analgesic effect than morphine (less potent) more lipophilic (more CNS) less affinity to receptor high bioavia
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codiene methoxy on c3 (usally anti tussive) less potent than morphine (less analgesic activity) more lipophilic increased CNS penetration