Pharmacology VIII

Description

Praxis Tests: Pharmacology Quiz on Pharmacology VIII, created by ACAPUN INSTITUTE on 08/11/2021.
ACAPUN INSTITUTE
Quiz by ACAPUN INSTITUTE, updated more than 1 year ago
ACAPUN INSTITUTE
Created by ACAPUN INSTITUTE over 2 years ago
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Resource summary

Question 1

Question
Atropine and propantheline exert their effects on peripheral structures by
Answer
  • a. preventing release of acetylcholine
  • b. preventing synthesis of acetylcholine
  • c. enhancing destruction of acetylcholine
  • d. competeing with acetylcholine for receptor sites
  • e. producing physiologic effects opposite to those of acetylcholine

Question 2

Question
Neostigmine produces its effect by physostigmine. These differ from the insecticides and nerve gases listed below in that they are reversible and can be used clinically; the latter are irreversible
Answer
  • a. depressing acetylcholinesterase release
  • b. inhibiting acetylcholinesterase activity
  • c. increasing the rate of acetylcholine synthesis
  • d. acting like acetylcholine at ganglionic sites
  • e. increasing the amount of acetylcholine released from nerve terminals

Question 3

Question
Organophosphate insecticides and nerve gases inhibit the action of which of the following enzymes?
Answer
  • a. adenylate cyclase
  • b. monoamine oxidase
  • c. phosphodiesterase
  • d. acetylcholinesterase
  • e. carbonic anhydrase

Question 4

Question
Drugs which are additive with or potentiate the effects of acetylcholine include (a) methacholine (b) scopolamine (c) pralidoxime (d) neostigmine (e) pilocarpine
Answer
  • 1. (a), (b), and (c)
  • 2. (a), (c), and (d)
  • 3. (a), (d) and (e)
  • 4. (b), (d), and (e)
  • 5. (c), (d) and (e)

Question 5

Question
Which of the following drugs is best to administer after poisoning by an organophosphate cholinesterase inhibitor?
Answer
  • a. atropine
  • b. phenytoin
  • c. pralidoxime
  • d. propantheline
  • e. phenobarbital

Question 6

Question
Which of the following compounds is a ganglionic blocking agent?
Answer
  • a. curarine
  • b. edrophonium
  • c. mecamylamine
  • d. succinylcholine
  • e. gallamine triethodide

Question 7

Question
Which of the following acts by antagonizing cholinesterase?
Answer
  • a. atropine
  • b. muscarine
  • c. neostigmine
  • d. pilocarpine
  • e. acetylcholine

Question 8

Question
When neostigmine is administered before acetylcholine, the action of acetylcholine will be
Answer
  • a. blocked
  • b. enhanced and prolonged
  • c. less intense and of shorter duration
  • d. none of the above. The action of acetylcholine is not affected by neostigmine

Question 9

Question
Neostigmine can stimulate denervated skeletal muscle because it
Answer
  • a. is a congener of acetylcholine
  • b. is a competitive blocking agent
  • c. has no effect on acetylcholinesterase
  • d. is more potent than diisopropylfluorophosphate
  • e. is capable of acting directly on the end-plate

Question 10

Question
Which of the following is used to prevent laryngospasm?
Answer
  • a. atropine
  • b. epinephrine
  • c. diazepam (Valium)
  • d. neostigmine (Prostigmine)
  • e. succinylcholine (Anectine)

Question 11

Question
In treating xerostomia, which of the following might be prescribed?
Answer
  • a. atropine
  • b. ephedrine
  • c. neostigmine
  • d. scopolamine
  • e. mecamylamine

Question 12

Question
Which of the following drugs is most likely to dry secretions in the oral cavity?
Answer
  • a. diazepam
  • b. promethazine
  • c. physostigmine
  • d. propantheline
  • e. diphenhydramine

Question 13

Question
The most useful drug to induce salivation is one which has properties that are
Answer
  • a. adrenergic
  • b. cholinergic
  • c. ganglionic blocking
  • d. adrenergic blocking
  • e. cholinergic blocking

Question 14

Question
Drugs that are commonly used in the control of excessive salivation include (a) meprobamate (b) atropine (c) methantheline (d) codeine (e) chlorpromazine
Answer
  • 1. (a) and (b) only
  • 2. (a), (b), and (c)
  • 3. (b) and (c) only
  • 4. (b), (c), and (d)
  • 5. (d) and (e)

Question 15

Question
Drugs that are commonly used in the control of excessive salivation include (a) meprobamate (b) atropine (c) methantheline (d) codeine (e) chlorpromazine
Answer
  • 1. (a) and (b) only
  • 2. (a), (b), and (c)
  • 3. (b) and (c) only
  • 4. (b), (c), and (d)
  • 5. (d) and (e)

Question 16

Question
Tachycardia in a patient administered with atropine or scopolamine results from
Answer
  • a. release of adrenal catecholamines
  • b. blockade of vagus nerve activity
  • c. blockade of the nicotinic cholinergic receptor
  • d. stimulation of the alpha adrenergic receptor
  • e. stimulation of the beta adrenergic receptor

Question 17

Question
All of the following are possible effects of cholinomimetic drugs except
Answer
  • a. mydriasis
  • b. bradycardia
  • c. increased peristalsis
  • d. stimulation of sweat glands
  • e. increased secretion by bronchial glands

Question 18

Question
A paralyzing dose of succinylcholine initially elicits
Answer
  • a. CNS stimulation
  • b. CNS depression
  • c. decreased salivation
  • d. muscle fasiculation
  • e. extrapyramidal reactions

Question 19

Question
Based on its known mechanism and sites of action, scopolamine should theoretically be useful in (a) treatment of peptic ulcer (b) providing euphoria and amnesia prior to surgery (c) relieving bronchoconstriction (d) relieving some of the symptoms of Parkinson disease (e) visualization of the retina
Answer
  • 1. (a), (b), (d) and (e)
  • 2. (a), (b), and (e) only
  • 3. (a),and (c)
  • 4. (b) and (e) only
  • 5. All of the above

Question 20

Question
Symptoms of poisoning by an organophosphate insecticide include all of the following except:
Answer
  • a. skeletal muscle fasiculation
  • b. excessive salivation
  • c. bronchoconstriction
  • d. hot, dry skin
  • e. diarrhea

Question 21

Question
All of the following symptoms are associated with neostigmine poisoning except
Answer
  • a. diarrhea
  • b. salivation
  • c. convulsions
  • d. bonchiolar constriction
  • e. skeletal muscle paralysis

Question 22

Question
Symptoms of atropine poisoning in man include (a) decreased intraocular pressure (b) burning dry mouth (c) nausea, vomiting and diarrhea (d) hyperthermia (e) orthostatic hypotension
Answer
  • 1. (a) and (c)
  • 2. (b) and (d)
  • 3. (b), (d), and (e)
  • 4. (d) and (e)
  • 5. All of the above

Question 23

Question
The most likely signs or symptoms of overdosage with atropine are
Answer
  • a. CNS excitation and tachycardia
  • b. intestinal cramps and diarrhea
  • d. ptyalism and increased sweating
  • e. constriction of the pupils and blurring of vision

Question 24

Question
Disorientation, confusion and hallucinations resulting from an overdose of scopolamine are most efficaciuosly treated by administering
Answer
  • a. atropine
  • b. levodopa
  • c. acetylcholine
  • d. physostigmine

Question 25

Question
The immediate cause of death from irreversible cholinesterase inhibitors is
Answer
  • a. shock
  • b. convulsion
  • c. cardiac arrhythmia
  • d. respiratory paralysis
  • e. dehydration from vomiting and diarrhea

Question 26

Question
Each of the following is a symptom of cholinergic crisis except
Answer
  • a. bradycardia
  • b. lacrimation
  • c. vasoconstriction
  • d. extreme salivation
  • e. weakness of voluntary muscles

Question 27

Question
Succinylcholine is a short-acting neuromuscular junction blocking agent useful for providing a brief paralysis to aid in intubating patients. It is short-acting because
Answer
  • a. it is subject to rapid metabolism in the liver
  • b. it rapidly redistributes away from the NMJ
  • c. it is subject to inactivation by plasma esterases
  • d. it undergoes rapid inactivation in the GI tract

Question 28

Question
Atropine-like drugs are classed as
Answer
  • a. anti-adrenergic
  • b. cholinomimetic
  • c. sympatholytic
  • d. anti-cholinergic
  • e. sympathomimetic
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