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Mutations and Transposable Elements

Trey von Gortler Englisch 21 Karten

Mutations and Transposable Elements

Karten in diesem Stapel (21)

  1. 1Somatic MutationA ______ in a _____ cell that gets carried on to a daughter cell via mitosis
  2. 2Germ-Line MutationA mutation in a _______ producing cell. is carried on to an entire organism during reproduction (about 1/2 population)
  3. 3Base Insertion, Deletion, SubstitutionThe three general types of mutations are ___, ____, & _____
  4. 4Frameshift_____: mutations in multiple of 3
    _____: Move the reading the frame
  5. 5Expanding Nucleotide Repeat Mutations (Diagram shows increased severity as more replications occur)The _____ Repeats, the less stable, the _____ likely to get out of control in future generations (________)Expanding Nucleotide Repeat Mutations (Diagram shows increased severity as more replications occur)
  6. 6Missense Mutation______ substitution that changes ______ in a protein
  7. 7Nonsense_______ substitution resulting in a premature ________
  8. 8Silent Mutations______ substitution that does not cause changes ______ in a protein
  9. 9Silent Mutations with Phenotypic EffectsAbundance of _______ can modify the rate of ________. (____accepting)
    _____ structure altered, can affect _____ due to interactions between bases
  10. 10Gain of Function MutationsThis mutation can be conditional (to certain environments) and lethal. Causes _____ in protein function and is usually _______
  11. 11Loss of Function MutationsThis mutation can be complete or partial in affect. Change in functional protein MUST be homozygous. Causes _____ in protein function.
  12. 12ForwardChanges the wild type phenotype into a _____ phenotype
  13. 13ReverseChanges the _____ type phenotype into a _____ phenotype by restoring the original ________type
  14. 14SuppressorChanges the _____ type phenotype into a _____ phenotype by altering the ________type at a different site from the original mutation
  15. 15IntragenicExamples:
    A second substitution that results in a different codon that codes for the same amino acid
    A second insertion or deletion that fixes a frameshift
    Intragenic
  16. 16IntergenicExamples:
    A second mutation on a gene coding for tRNA that causes a tRNA carrying lys to bind with the mutated stop codon instead of early termination
    Intergenic
  17. 17TransitionPurine - ______, Prymadine - _____
  18. 18TransversionPurine - Pryamdine
  19. 19Non-Watson & Crick BasepairingResult of weak ________ bonding events that occurs during ______ of DNA
  20. 20Strand Slippage New Strand Template Strand______ in the DNA causing nucleotides to loop out of the DNA
    Insertion when occuring in ______
    Deletion when occuring ______
  21. 21Crossing Over______ during prophase of Meiosis 1 can cause _______ & __zx_____

Informationen

Beschreibung
Lectures from Week of Oct 2nd
Erstellt von
Trey von Gortler · Okt 2017
Aktualisiert
7 Okt 2017
Aufrufe
124
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