Flashcards
Mutations and Transposable Elements
Flashcards do conjunto (21)
- 1Somatic MutationA ______ in a _____ cell that gets carried on to a daughter cell via mitosis
- 2Germ-Line MutationA mutation in a _______ producing cell. is carried on to an entire organism during reproduction (about 1/2 population)
- 3Base Insertion, Deletion, SubstitutionThe three general types of mutations are ___, ____, & _____
- 4Frameshift_____: mutations in multiple of 3
_____: Move the reading the frame - 5Expanding Nucleotide Repeat Mutations (Diagram shows increased severity as more replications occur)The _____ Repeats, the less stable, the _____ likely to get out of control in future generations (________)
- 6Missense Mutation______ substitution that changes ______ in a protein
- 7Nonsense_______ substitution resulting in a premature ________
- 8Silent Mutations______ substitution that does not cause changes ______ in a protein
- 9Silent Mutations with Phenotypic EffectsAbundance of _______ can modify the rate of ________. (____accepting)
_____ structure altered, can affect _____ due to interactions between bases - 10Gain of Function MutationsThis mutation can be conditional (to certain environments) and lethal. Causes _____ in protein function and is usually _______
- 11Loss of Function MutationsThis mutation can be complete or partial in affect. Change in functional protein MUST be homozygous. Causes _____ in protein function.
- 12ForwardChanges the wild type phenotype into a _____ phenotype
- 13ReverseChanges the _____ type phenotype into a _____ phenotype by restoring the original ________type
- 14SuppressorChanges the _____ type phenotype into a _____ phenotype by altering the ________type at a different site from the original mutation
- 15IntragenicExamples:
A second substitution that results in a different codon that codes for the same amino acid
A second insertion or deletion that fixes a frameshift
- 16IntergenicExamples:
A second mutation on a gene coding for tRNA that causes a tRNA carrying lys to bind with the mutated stop codon instead of early termination
- 17TransitionPurine - ______, Prymadine - _____
- 18TransversionPurine - Pryamdine
- 19Non-Watson & Crick BasepairingResult of weak ________ bonding events that occurs during ______ of DNA
- 20Strand Slippage New Strand Template Strand______ in the DNA causing nucleotides to loop out of the DNA
Insertion when occuring in ______
Deletion when occuring ______ - 21Crossing Over______ during prophase of Meiosis 1 can cause _______ & __zx_____
Informações
- Descrição
- Lectures from Week of Oct 2nd
- Criado por
- Trey von Gortler · out 2017
- Atualizado
- 7 out 2017
- Visualizações
- 124
- Avaliação