Karteikarten
Pharmacology notes 1
Karten in diesem Stapel (21)
- 1Why was Curare found to be useful by anesthetists?Because the drug acts as a muscle relaxant. It prevents muscle contraction. So long as the patient is ventilated throughout, they will be relaxed and easy to operate on during surgery.
- 2Acetlycholine is a nicotinic ______?Agonist.
- 3Curare in various forms is a nicotinic _____?Antagonist. It is a non-depolarising neuromuscular blocking agent at nicotinic receptor sites.
- 4Define Pharmacology:The study of the interaction between exogenous chemicals (xenobiotics) and living organisms.
- 5How might an organism affect a xenobiotic?Through transport, distribution and metabolism of the xenobiotic.
- 6How might a xenobiotic affect an organism?By molecular targets, mode of action and toxicology within the organism.
- 7Define drug:A chemical taken that is intended to modulate the current physiological status quo.
- 8Define ligand:A compound that binds to another molecule, e.g. a receptor for a protein.
- 9What is Bioavailability?The amount or proportion of a drug that becomes available to the body following its administration.
- 10What is Pharmacokinetics?What the body does to a drug.
- 11What is Pharmacodynamics?What a drug does to the body.
- 12The first written knowledge of materials that could relieve pain/alter moods/perception etc. date back to when and where?Approx. 2700 B.C. in China. Pen Tsao - described uses and classifications of medicinal plants.
- 13In 1550 B.C. written prescriptions and similar medical advances were present in:Ancient Egypt, Babylonia and India. (400-300 B.C. the Greeks made huge pharmacological advances.)
- 14What was the Doctrine of Signatures?Assumption that herbs that resembled parts of the body could be used to treat ailments there.
- 15What does mandrake root contain that gives it anti-cholinergic properties?Atropine, scopolamine and hyoscyamine. Acts as a hallucinogen and hyponotic.
- 16Why might the plant datura also have these effects?Flowers and fruit contain anti-cholinergics also; atropine, scopolamine and hyoscyamine.
- 17What important pharmacological advances arose in the 19th century?Knowledge to provide pure compounds and allow careful monitoring of their physiological effects.
- 18What drug does the opium poppy provide?Morphine for analgesia.
- 19What drug did the mandrake root provide?Scopolamine for sedation and anaesthesia.
- 20What drug did the coca leaf provide?Cocaine for local anaesthesia.
- 21Salicin (isolated from willow) led to the development of what drug?Acetylsalicyclic acid/aspirin. Related compound with less side effects.
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- Karteikarten am Pharmacology notes 1, erstellt von mereana.matairan am 19/10/2014.
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- mereana.matairan · Okt 2014
- Aktualisiert
- 10 Nov 2016
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