Randomized Crossover trials

Randomized Crossover trials

1. target population

   • Exclued (reason)
   • Inclued (potential participants
     • Informed consent
       • Don't participate
       • Participants
         • Basal assessment
           • Randomization
             • Sequence A
               • Intervention A
                 • Wash out period
                   • Intervention B
                     • Wash out period
                       • Diference between assessment
             • Sequence B
               • Intervention B
                 • Whash out period
                   • Intervention A
                     • wash out period
                       • Diference between assessment
             • Final Assessment I
               • Basal assessment II
                 • Final assesment II
                   • Hupotesis testing, P value? intrasubject comparision