Amelogenisis

Amelogenisis

1. Enamel, 96% mineral, contains hydroxiapitite rods

2. Ameloblasts

   • derived from internal dental epithelium
     • Secrete enamel proteins,amelogenins 90%, amelin 5-10%

3. Has no blood supply, denpends on Glycogen and extracelluar matrix

   • Phase 1+2
     • A matrix is secreted and partially mineralised immediatly
       • Completed with complete mineralisaion, removal of organic material. Maturation phase.
     • Starts only after Odontoblasts start to lay dentine.
       • contains no collagen
         • Ameloblasts move away from dentine surface, and produce a short conical process called 'Tomes Process'
           • Secretion starts at proximal end of Tomes, walled pits form and then filled in from other end of Tomes
     • 3. Rebound to surface
       • 4. The outamost 5um become highly mineralised

4. Very sensitive, tetricyclin staining, flourosis etc.