LIVER

LIVER

1. Gross Anatomy

   • Abdo. location
   • 4 Lobes
   • 8 segments
   • 5 Ligaments
   • Vasculature
   • CT
   • lymphatic
   • Portal Triad

2. Microstructure

   • Histology
     • Hepatocyte
       • 3 surfaces
     • Endothelial cells
     • Kupffer cells
     • Perisinusoidal cells
     • Space of Disse
     • Canal of Herings
     • LAL
   • Hepatic lobule
   • Portal lobule
   • Hepatic acinus

3. Function

   • Metabolic disorders
   • Carb. Lipid. Protein metabolism
   • Detox
     • Alcohol metabolism
   • Biotransformation & Excretion

4. BILE

   • BILIRUBIN
     • Characteristics
     • Synthesis
     • Conjugation
     • Metabolism & enterohepatic circulation
   • BILE ACID
     • Function
     • Syn. & Reab.
     • Secretion mechanism
     • Chem prop. & emulsification
   • GB & Biliary tree
     • Anatomy
     • Contraction regulation mechanism
     • Gall stones
       • Types
       • Pathophysiology
       • Complications
   • Jaundice
     • Classification
     • Causes
     • Clinical features
     • Treatment
     • Investigation/LFT
     • complication
   • composition
   • Function
   • excretion rate

5. Portal HTN

   • Causes
   • Clinical features
   • Investigations
   • Managements

6. Alcoholic Liver Disease

   • Steatosis
     • Cause
     • Clinical history
   • Alcoholic hepatitis
     • Fibrosis
     • Clinical history
   • Cirrhosis
     • Definition
     • Signs & symptoms
     • Pathophysiology
     • Complications
       • Liver Failure
     • Causes
     • management