Zusammenfassung der Ressource
I always feel fatigued and tired
- Causes of fatigue
- Post viral infection
- Endocrine
- Hypothroidism
- Addisons
- Organ failure
- Heart failure
- Neoplastic
- Chronic infecetion
- TB
- Chronic inflammatory diseases
- Crohn's disease
- Physiology of defecation
- Several steps
- Types of colorectal cancer
- Squamous cell carcinoma
- Cloacogenic carcinoma
- Adenocarcinoma
- Rare
- Basal cell carcinoma
- Melanoma
- Risk factors
- Age
- Male gender
- Smoking
- Obesity
- Heriditary polyposis syndromes
- First degree relatives with colon cancer
- Diet factors
- Pathogenesis
- Two pathways
- Adenoma-carcinoma sequence
- Mutation of both copies of APC
- K-ras mutation
- P53 mutation and increased COX 2
- Carcinoma
- Polyp formation
- Increased risk for polyp
- MSI
- Mutations of mismatch repair enzyme
- Accumalation of several mutation
- Signs and symptoms
- Change in bowel habits
- Difficulty in relieving oneself
- Rectal bleeding
- Cramping
- Fatigue
- Unintentional weight loss
- Investigations
- Colonscopy
- CT scan
- Laboratory tests
- CBC
- Tumor markers
- CEA
- Staging and grading
- Mangement
- FOLFOX
- 5-Flurouracil
- Leucoverin
- Oxaloplatin
- CAPOX
- Capcitabeine
- Surgical
- Excision of the mass
- Local
- Total
- Screening
- Age 45 and above
- Relatives with colorectal cancer
- Epidemiology
- Anatomy of large intestine