Module 1 Neuro Development

Module 1 Neuro Development

1. 1) induction of neural map

   • stem cells: divide
   • plate folds ----neural tube

2. 2) neural proliferation

3. 3) migration and aggregation

   • radial and tangential migrations
     • straight line to outer wall
     • parallel to wall
   • somal translocation and glial mediated
     • extension grows out--cell moves---retracts
     • cells move along radial glial cells

4. 4) axon growth and synapse formation

   • chemo affinity theory: each site releases different chemicals to attract correct axon

5. 5) neuron death and synapse rearrangement

   • apoptosis---active
   • necrosis---passive---dnagerous