Biomaterials (Introduction)

Applications
1. Biomedical implants used in entire body: -Temporary: Plasters, contact lens, -Degradable: Sutures, -Permanent: Pacemakers, joint replacement
  1. Clinical needs: 1. Heart diseases: Pace maker, 2. Diabetes: Drugs Deliver, 3. Road traffic accidents: Body parts transplant or implant
  2. Tissue Engineering
    1. Development of biological substitutes that restore, maintain, or improve tissue function
    2. Tissue Grafting
      1. Autograft
        Tissue transplanted from the same host. Donor = host
      2. Allograft
        Transplant of tissue or organ from the same species with different genotype
      3. Xenograft
        Graft from a different species. Eg; animal to human
  3. Grades of Medical Implants
    1. CE Marking
    2. FDA Grades
2. Transplantation
  1. Advantages
    1. Long-term solution
    2. Architecture
    3. Functional
  2. Disadvantages
    1. Expensive
    2. Limited supply
    3. Ethics issues
    4. Immuno-supressant
3. Implantation
  1. Advantages
    1. Low cost
    2. High supply
    3. Customizable
    4. Reproducible
  2. Disadvantages
    1. Short-term
    2. Adverse effects; rusting
What?
1. A biomaterial is a nonviable material used in a medical device, intended to interact with biological system
  1. Key: "Biocompatibility" - Ability of a material to perform with an appropriate host response in a specific application.
    1. Eg; Resistance to blood clot, bacterial colonization and uncomplicated healing
    2. -Intimate contact with host / living tissue - Does not cause any adverse effects on host tissues or organs
History

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Biomaterials (Introduction)

Beschreibung

Zusammenfassung der Ressource

Medienanhänge

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