Lecture 1

Lecture 1

1. Functions of TMS

   • Offline (after effects)
     • Modulation
   • Online (event related)
     • Stimulation
       • Motor evoked potential
       • Phosphene
     • Disruption

2. Physics

   • Maxwell-Faraday equation
     • Time varying magnetic field
       • Electric magnetic field
   • TMS pulse shape
     • Monophasic
     • Biphasic
       • Biphasic has a change to a negative and this makes a bigger difference and since it is the rate of change that matters, so biphasic elicits bigger signal.
   • Magnetic field vs distance
     • Exponential decrease with increasing distance
   • Coil geometry
     • Circular
     • 8 shape
       • More focal
         • it is more focal because the intensity is around the edges of the shape, so if you put two circular coils you get the biggest activity between them
         • Less deep
           • The more focal you could get, the less deep you could go.

3. Physiology

   • Membrane potential
     • Action potential
   • TMS protocols
     • Single pulse
     • rTMS

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