Absorption - created from Mind Map

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physiological factors

formulation factors

physical-chemical factors

membrane physiology

passage of drug across membranes

gastrointestinal physiology

memprane structure

phospholipid bilayer

cholesterol

proteins

channel protien

carrier protien

receptor protien

enzyme protien

cell-recognition protien

cell adhision protien

paracellular

transcellular

passive diffusion

endocytosis

pore transport

ion pair formation

carrier mediaed

facilitated diffusion

active transport

p-glyco protien

GIT physiology &drug absorption

Gastric emptying time & motility

effect of food on drug absorption

entrohepatic circulation

first pass effect

sloutions

suspintions

capsules

tablets

coated

un coated

PH- partition theory

lipid solubility of drug

dissolution and ph

salts

crystal form

drug stability & hydrolysis in GIT

complexation

adsorption