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PHSI3011 13-1 Circadian Rhythm and Disease

Gelöschter Nutzer 11 Fragen Aktualisiert am 10 Nov 2017

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  1. 1The SCN is [primarily?] responsible for heaps of the Circadian Rhythm stuff. What is it?
    1. ASagittal Central Nucleus
    2. BSupraCentral Nucleus
    3. CSagittal Cortical Nucleus
    4. DSupraCortical Nucleus
    5. ESupraChiasmal Nucleus
    6. FSagittal Chiasmal Nucleus
  2. 2The CLOCK and BMAL1 genes are downregulated through negative feedback from which of the following?
    1. APER
    2. BCRY
    3. CRORa
    4. DCCGs
  3. 3Deepest sleep [normally] occurs at what time?
    1. A12am
    2. B1am
    3. C2am
    4. D3am
    5. E4am
    6. F4:30am
    7. G6am
    8. H6:30am
  4. 4Jet lag results in a desynchrony between the sleep-wake cycle and the Melatonin rhythm on:
    1. ABlood transcriptome
    2. BPlasma transcriptome
    3. CRenal transcriptome
    4. DMitochondrial transcriptome
  5. 5Human circadian rhythm disorders that maintain a stable entrainment in relation to the 24-hour day-night cycle include:
    1. ADelayed Sleep Phase Disorder (DSPD)
    2. BAdvanced Sleep Phase Disorder (ASPD)
    3. CNon-24-Hour Sleep-Wake Syndrome
    4. DIrregular Sleep-Wake Rhythm (ISWR)
    5. EShift Work Sleep Syndrome
    6. FTime Zone Change Syndrome
    7. GFree-Running Disorder (FRD)
  6. 6Free-Running Disorder (FRD) is:
    1. AA progressive pattern of 1- to 2- hour delays in sleep onset and wake times
    2. BTemporally disorganised and variable episodes of sleeping and waking behaviour with short sleep periods of a few hours that are distributed randomly through the day and night
    3. CSomnambulism
    4. DSleepwalking
  7. 7The endogenous cycle is how many hours?
    1. A23
    2. B24
    3. C25
  8. 8Mutations in CLOCK or PER3 can result in Delayed Sleep Phase Disorder (DSPD). This has been associated with metabolic & psychiatric disorders (e.g. depression, schizophrenia), but is also associated with which of the following:
    1. AExtreme eveningness preference
    2. BExtreme morningness preference
  9. 9Treatments of human circadian rhythm disorders include:
    1. ATimed melatonin administration
    2. BPhase resetting – bright light administration
    3. CMelatonin agonists
    4. DToughening the fuck up
  10. 10Disruption of circadian rhythms can lead to:
    1. AMetabolic Imbalance
    2. BDisruption in melatonin levels
    3. CDisruption in blood glucose levels
    4. DInsulin resistance
    5. ECrankiness

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Beschreibung
PHSI3011 13-1 Circadian Rhythm and Disease
Autor
Gelöschter Nutzer
Sprache
English
Aufrufe
25
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Erstellt am 31 Okt 2017 · aktualisiert am 10 Nov 2017
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