Test
PHSI3011 13-1 Circadian Rhythm and Disease
Preguntas del test (11)
1The SCN is [primarily?] responsible for heaps of the Circadian Rhythm stuff. What is it?
- ASagittal Central Nucleus
- BSupraCentral Nucleus
- CSagittal Cortical Nucleus
- DSupraCortical Nucleus
- ESupraChiasmal Nucleus
- FSagittal Chiasmal Nucleus
2The CLOCK and BMAL1 genes are downregulated through negative feedback from which of the following?
- APER
- BCRY
- CRORa
- DCCGs
3Deepest sleep [normally] occurs at what time?
- A12am
- B1am
- C2am
- D3am
- E4am
- F4:30am
- G6am
- H6:30am
4Jet lag results in a desynchrony between the sleep-wake cycle and the Melatonin rhythm on:
- ABlood transcriptome
- BPlasma transcriptome
- CRenal transcriptome
- DMitochondrial transcriptome
5Human circadian rhythm disorders that maintain a stable entrainment in relation to the 24-hour day-night cycle include:
- ADelayed Sleep Phase Disorder (DSPD)
- BAdvanced Sleep Phase Disorder (ASPD)
- CNon-24-Hour Sleep-Wake Syndrome
- DIrregular Sleep-Wake Rhythm (ISWR)
- EShift Work Sleep Syndrome
- FTime Zone Change Syndrome
- GFree-Running Disorder (FRD)
6Free-Running Disorder (FRD) is:
- AA progressive pattern of 1- to 2- hour delays in sleep onset and wake times
- BTemporally disorganised and variable episodes of sleeping and waking behaviour with short sleep periods of a few hours that are distributed randomly through the day and night
- CSomnambulism
- DSleepwalking
7The endogenous cycle is how many hours?
- A23
- B24
- C25
8Mutations in CLOCK or PER3 can result in Delayed Sleep Phase Disorder (DSPD). This has been associated with metabolic & psychiatric disorders (e.g. depression, schizophrenia), but is also associated with which of the following:
- AExtreme eveningness preference
- BExtreme morningness preference
9Treatments of human circadian rhythm disorders include:
- ATimed melatonin administration
- BPhase resetting – bright light administration
- CMelatonin agonists
- DToughening the fuck up
10Disruption of circadian rhythms can lead to:
- AMetabolic Imbalance
- BDisruption in melatonin levels
- CDisruption in blood glucose levels
- DInsulin resistance
- ECrankiness
11True or false: Circadian rhythm disruptions have been linked to cancer.
- ATrue
- BFalse
- C...true AND false.
Información
- Descripción
- PHSI3011 13-1 Circadian Rhythm and Disease
- Autor
- Usuario eliminado
- Idioma
- English
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- Historial
- Creado el 31 oct 2017 · actualizado el 10 nov 2017
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