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NE7.5 Cognitive enhancers

Gelöschter Nutzer 5 Fragen Aktualisiert am 11 Okt 2019

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  1. 1Age related changes to cognitive function:
    - Declining performance of: [blank_start]speed[blank_end] of processing, working memory, [blank_start]long[blank_end]-term memory
    - Preserved performance of: [blank_start]world knowledge[blank_end]

    Mild cognitive impairment affects 10-20% of people >[blank_start]65[blank_end] years, and affects [blank_start]men[blank_end] more than women. It is associated with [blank_start]depression[blank_end], polypharmacy, and uncontrolled [blank_start]CV[blank_end] risk factors.
    1. Aspeed
    2. Blong
    3. Cworld knowledge
    4. D65
    5. Emen
    6. Fdepression
    7. GCV
  2. 2Which of these is not a symptom of mild cognitive impairment? (MCI)
    1. ADiffiuclty in decision making
    2. BPoor concentration
    3. CDiffiuclty in abstract thinking
    4. DDifficulty in finding the right word
    5. ENeglect of hygiene and/or nutrition
    6. FMore impulsive
    7. GEasily distracted
    8. HForget important events
    9. IMood fluctuations
  3. 3Which of these is not a cognition enhancing drug?
    1. ACaffeine
    2. BNicotine
    3. CAmphetamines
    4. DCannabinoids
  4. 4Treatment options are related to neurotransmitters in the brain regions controlling learning and memory, and temporarily improve dementia symptoms.

    [blank_start]Cholinesterase[blank_end] inhibitors:
    - E.g. donepezil, galantamine, rivastigmine
    • For [blank_start]mild[blank_end]-moderate cognitive symptoms
    • SEs: [blank_start]Nausea, vomiting, diarrhoea,[blank_end] dyspepsia; urinary incontinence; dizziness
    • Serious SEs: [blank_start]heart[blank_end] block and sinus [blank_start]bradycardia[blank_end]

    [blank_start]Glutamate antagonist[blank_end] ie Memantine
    • Moderate-[blank_start]severe[blank_end] cognitive symptoms OR when cholinesterase inhibitors [blank_start]contraindicated[blank_end]
    • SEs: c[blank_start]onstipation, hypertension, dyspnoea,[blank_end] headache, dizziness, drowsiness
    1. ACholinesterase
    2. BGlutamate antagonist
    3. Cmild
    4. DNausea, vomiting, diarrhoea,
    5. Eheart
    6. Fbradycardia
    7. Gsevere
    8. Hcontraindicated
    9. Ionstipation, hypertension, dyspnoea,
  5. 5Nootropics or ‘smart drugs’:
    1. [blank_start]Methylphenidate[blank_end]
    • Rx: narcoplepsy, ADHD, ADD
    • Blocks DA reuptake
    2. [blank_start]Modafinil[blank_end]
    • Rx: narcolepsy
    • Mechanisms unclear (wake promoting neurons in tuberomammillary nucleus, DAT)
    3. [blank_start]Piracetam[blank_end]
    • Rx: essential tremor (section 29)
    • Facilitates cholinergic, dopaminergic, noradrenergic neurotransmission

    Long term side effects are unclear.
    Short term:
    [blank_start]headache, dizziness, nausea[blank_end], [blank_start]psychiatric[blank_end] disorders, [blank_start]cardiovascular[blank_end] symptoms
    1. AMethylphenidate
    2. BModafinil
    3. CPiracetam
    4. Dpsychiatric
    5. Eheadache, dizziness, nausea
    6. Fcardiovascular

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Beschreibung
Der Nutzer hat seine Fachbereichs-Information gelöscht. Quiz am NE7.5 Cognitive enhancers, erstellt von Gelöschter Nutzer am 11/10/2019.
Autor
Gelöschter Nutzer
Sprache
English
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49
Verlauf
Erstellt am 11 Okt 2019 · aktualisiert am 11 Okt 2019
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