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Allgemeine und molekulare Genetik 2

Anna Ullrich 13 Fragen 5,0 (1 Bewertung) Aktualisiert am 24 Sep 2016

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  1. 1What's right: Synthetic lethality ...
    1. ACombinatorial effects between alleles or substances
    2. BEffects in synthetic biology
    3. CAn effect specific to a double mutation (not seen in the singles)
    4. DAn effect specific to a mutation in combination with a SMI-small molecule inhibitor (not seen by either mutation or SMI alone)
  2. 2What's right: Phage lambda lysogen ...
    1. AC1 represses lambda's lysogenic genes, c2 activates int- and c1 transcription, c3 stabilizes c2
    2. BC1 represses lambda's lysogenic genes, c2 represses int- and c1 transcription, c3 destabilizes c2
    3. CC1 represses lambda's lytic genes, c2 activates int- and c1 transcription, c3 stabilizes c2
    4. DC1 represses lambda's lytic genes, c2 represses int- and c1 transcription, c3 destabilizes c2
  3. 3What's right: Bacterial transformation
    1. AThe mechanism of gram+ and gram- DNA uptake is not related
    2. BGram- bacteria possess an outer membrane requiring an additional pore for DNA uptake
    3. CGram+ bacteria possess an outer membrane requiring an additional pore for DNA uptake
    4. DGram+ and gram- bacteria have a pilus structure, a dsDNA receptor and an inner membrane pore in common
  4. 4What's right: Intra- vs extragenic complementation
    1. AGenetic complementation between mutations in different genes does not require wild type alleles
    2. BExtragenic complementation is rare and requires mutations in different functional domains
    3. CIntragenic complementation is rare and depends on the presence of domains that function independently
    4. DMolecular complementation depends on addition of the wild gene
  5. 5What's right: Dominant vs epistatic
    1. Aa is epistatic to locus b , if the double mutant (a,a/b,b) has the same phenotype as the single mutant (a,a)
    2. Ba is epistatic to b, means: Pht(a,b)=Pht(a,B) .. (although Pht(A,b)≠Pht(A,B))
    3. Cdominant : Pht(A,A)=Pht(a,A)
    4. Ddominant relates alleles of 1 gene, epistatic relates an allele to another gene
    5. EA is dominant over a: Pht(a,A) = Pht(a,a)
  6. 6What's right: gene vs allele
    1. Aa ncRNA is not encoded by a gene, because it is not translated
    2. Ba centromere is not a gene, because it is not transcribed
    3. Ca bacterial cistron is not a gene, because it contains several functional units
    4. Da gene is a functional unit in the genome, activated by transcription while an allele is a sequence variant of a
      gene
    5. Ea bacterial operon is not a gene, because it contains several functional units
  7. 7What's right: Falsifyability
    1. AAccording to Popper’s critical rationalism (P.c.r), a Sc.Hyp can’t be claimed true, without evidence
    2. BAccording to P.c.r. a single experiment, if well performed, can prove a hypothesis forever
    3. CAccording to P.c.r. a single experiment, if well performed, can disprove a hypothesis forever
    4. DAccording to P.c.r. a scientific hypothesis must make a prediction, which can be proven wrong
  8. 8What's right: Suppressor mutation
    1. AA suppressor mutation blocks the expression of another gene
    2. BA suppressor mutation can’t occur in the same gene
    3. CA suppressor mutation must occur in tRNA
    4. DA suppressor blocks the appearance of a mutant phenotype
  9. 9What's right: What is the phenotype?
    1. AMany genes do not cause a phenotype
    2. BThe phenotype of a given mutation must be detectable under all conditions
    3. CThe phenotype of a mutation can change according to the situation
    4. DThe phenotype ist the observable impact of an allele
  10. 10Connect the topic with the correct boxes/key words ...
    BACTERIAL RECOMBINEERING
    1. AattB/P/L/R
    2. Btargetted DSB
    3. CRE enzyme free assembly of bacterial, genome-size DNA
    4. DEfficient, RE enzyme free transfer of inserts between plasmids
    5. EInhibition of RecBCD
    6. FRE enzyme free sub cloning from large inserts
    7. GRE enzyme free correction of genetic defects in vivo
    8. HBacterial immune system
    9. IExo, Beta, Gam
    10. JEdition through DSB-repair

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Beschreibung
Bachelor Mikrobiologie Quiz am Allgemeine und molekulare Genetik 2, erstellt von Anna Ullrich am 15/09/2016.
Sprache
Deutsch
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22
Verlauf
Erstellt am 15 Sep 2016 · aktualisiert am 24 Sep 2016
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5,0 von 5 · 1 Bewertung
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