Neurodeg2

Beschreibung

Biologie Quiz am Neurodeg2, erstellt von Mak Sch am 30/11/2017.
Mak Sch
Quiz von Mak Sch, aktualisiert more than 1 year ago
Mak Sch
Erstellt von Mak Sch vor mehr als 6 Jahre
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Zusammenfassung der Ressource

Frage 1

Frage
Question 1. Infection-like process related to assembled Aβ, tau and α-synuclein has the following characteristics
Antworten
  • A. Protein misfolding begins in specific regions
  • B. Pathological assemblies of misfolded protein spread to other areas
  • C. Prion-like process
  • D. All of the above

Frage 2

Frage
Question 2. The following are the main risk factors for cognitive decline and dementia, except:
Antworten
  • A. Traumatic brain injury
  • B. Obesity and diabetes
  • C. Hypertension
  • D. Education

Frage 3

Frage
Question 3. In some individuals at early stages of Alzheimer disease there is a:
Antworten
  • A. Severe loss of parietal cortical neurons
  • B. Severe loss of entorihnal cortex neurons
  • C. Severe loss of occipital cortical neurons
  • D. Severe loss of all cortical neurons

Frage 4

Frage
Question 4. The author of this lecture proposes a glial hypothesis of the origin of normal aging. This hypothesis says that:
Antworten
  • A. Synaptic atrophy is driven by astrocyte activation
  • B. Increase of transcription of GFAP
  • C. Age impairment of neurite growth reversed by SiRNA diminishing GFAP in old astrocytes
  • D. All of the above

Frage 5

Frage
Question 5. Age and Alzheimer changes in amyloidosis and neurodegeneration are related to the presence of the number of copies of a cholesterol transporter :
Antworten
  • ApoE4
  • PS1
  • APP
  • PS2

Frage 6

Frage
Recent research proposes that aging cortical atrophy is most probably due to:
Antworten
  • A. Loss of a huge number of small neurons
  • B. Neuron schrinkage
  • C. Loss of large neurons
  • D. Astrocyte loss

Frage 7

Frage
Question 7. Supported by strong evidence we recognize now as main factors to decrease risk of cognitive decline and dementia: (more than one answer possible)
Antworten
  • B. Education
  • C. Being vegetarian
  • D. Physical activity
  • A. Moderate Alcohol consumption

Frage 8

Frage
Question 8. Normal aging includes the decline of all these processes, except:
Antworten
  • A. Eye-blinking conditioning
  • B. EEG response time auditory response to auditory stimulus
  • C. Axonal conduction speed
  • D. Verbal memory

Frage 9

Frage
Question 9. During normal aging in the cerebral cortex:
Antworten
  • A. Decrease the numbers of astrocytes
  • B. Decrease the numbers of entorhinal cells
  • C. Increase the number of astrocytes
  • D. Increase the number of olygodendrocytes

Frage 10

Frage
Question 10. Normal aging of the brain includes: (more than one answer possible)
Antworten
  • A. Atrophy of cerebral cortex
  • B. Fast loss of cognitive of processes
  • C. Loss of synapses
  • D. Accumulation of amyloid

Frage 11

Frage
Question 11. Which of the following Alzheimer related genes are not involved in familiar early onset of the disease:
Antworten
  • D. Chromosome 21 APP gene
  • C. Chromosome 19 ApoE gene
  • B. Chromosome 14 PS-1 gene
  • A. Chromosome 1 PS-2 gene
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