15964104
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Quiz von Med Student , aktualisiert more than 1 year ago
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Erstellt von Med Student
vor mehr als 5 Jahre
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Frage 1
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According to their mechanism of action the adrenergic agonists can be divided in:
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direct agonists
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indirect agonists
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agonists with mixed mechanism of action
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natural compounds
Frage 2
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α1-adrenoceptors are located on:
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presynaptic neuronal endings
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postsynaptic neuronal endings
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blood vessels
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iris dilator muscle
Frage 3
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β1-adrenoceptors are located on:
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postsynaptic neuronal endings
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presynaptic neuronal endings
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myocardial cells
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juxtaglomerular apparatus in the kidney
Frage 4
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β2-adrenoceptors are located on:
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postsynaptic neuronal endings
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bronchial smooth muscles
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liver
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uterus (womb)
Frage 5
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β3-adrenoceptors are located in:
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adipose tissue
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urinary bladder
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presynaptic neuronal endings
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bronchial smooth muscles
Frage 6
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Pharmacological effects of Epinephrine are:
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positive chronotropic effect
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blood pressure elevation
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bronchial smooth muscles dilation
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elevated levels of blood sugar
Frage 7
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Indications for the clinical use of Epinephrine are:
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anaphylactic shock
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hypoglycaemia
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arrhythmia
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glaucoma with wide iridocorneal angle
Frage 8
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Potential adverse drug reactions of Epinephrine are:
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hypoglycaemia
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arrhythmia
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tremor
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anxiety and restlessness
Frage 9
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Clinical indications for prescribing α1-agonists are:
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arterial hypotension
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acute rhinitis
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asthma attack
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heart block
Frage 10
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Pharmacological effects of the selective β2-agonists are:
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pupillary dilation
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bronchial dilation
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blood pressure elevation
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relaxation of uterine muscle
Frage 11
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Which of the following drugs are selective β2-agonists?
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lsoprenalini sulfas
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Orciprenalini sulfas
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Salbutamol
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Salmeterol
Frage 12
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β2-agonists are indicated in:
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bronchial asthma
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digitalis intoxication
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arterial hypertension
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threatening abortion
Frage 13
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Adverse drug reactions of β2-agonists are:
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finger tremor
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bronchial dilatation
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hyperglycemia
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tolerance
Frage 14
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What are the main features of the indirect-acting adrenergic agonists?
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stimulation of central nervous system
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drug tolerance and dependence
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have no effect on the cardio-vascular system
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used for treatment of narcolepsy and attention deficiency hyperactivity disorder (ADHD)
Frage 15
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Clinically desirable interactions can occur between β2-agonists and:(find correct answer)
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tricyclic antidepressants
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inhaled corticosteroids
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inhaled antimuscarinic drugs
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beta blockers
Frage 16
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Mechanisms of action of the presynaptic adrenolytics are:
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blockade of the presynaptic α2-receptors
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activation of the presynaptic α2-receptors
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conversion to a “false“ neurotransmitter
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blockade of the phosphodiesterase enzyme
Frage 17
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Which of the following drugs act as agonists of the presynaptic α2-adrenoceptors?
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Salbutamol
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Clonidini hydrochloridum
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α-Methyldopum (Dopegyt)
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Sotalol
Frage 18
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Pharmacological effects of Clonidin are:
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decreased peripheral vascular resistance
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antihypertensive
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inhibition of gastric secretion
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antiarrhythmic
Frage 19
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Adverse drug reactions of Clonidin are:
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Dry mouth
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Drowsiness and depression
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Hypertensive attacks following abrupt cessation of treatment
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CNS stimulation
Frage 20
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For Methyldopa is true:
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has antihypertensive effect
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it is safe in pregnancy
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could cause drug-induced parkinsonism
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used to treat threatening abortion
Frage 21
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Which of the following drugs are α1-adrenoblockers?
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Prazosin
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Doxazosin
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Clonidin
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Chlorpromazin
Frage 22
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Pharmacological effects of Prazosin are:
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dilation of the resistive and capacitive vessels
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antihypertensive
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relaxation of the muscles in the prostate and bladder neck
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hyperglycaemia
Frage 23
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Adverse drug reactions of α1-adrenoblockers are:
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orthostatic collapse
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hypokalemia
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fluid retention
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hypoglycaemia
Frage 24
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Which of the following drugs are non-selective β-blockers?
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Atenolol
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Pindolol
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Acebutolol
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Propranolol
Frage 25
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Which of the following drugs are selective β1-blockers?
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Atenolol
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Pindolol
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Propranolol
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Metoprolol
Frage 26
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β-blockers are indicated in case of:
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hypertension
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bronchial asthma
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arrhythmia
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ischaemic heart disease
Frage 27
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Pharmacological effects of B-blockers are:
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bronchodilation
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negative inotropic effect
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positive chronotropic effect
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negative chronotropic effect
Frage 28
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β-blocker approved for topical use in treatment of glaucoma is:
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Bisoprolol
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Metoprolol
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Timolol
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Propranolol
Frage 29
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When applied topically in the eye the B-blocker Timolol will:
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increase the intraocular pressure
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decrease the intraocular pressure
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cause miosis
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cause mydriasis
Frage 30
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Potential adverse drug reactions of β-blockers are.
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hypoglycaemia
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bronchoconstriction
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hyperglycaemia
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nightmares
Frage 31
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For long-term treatment with β-blockers is true:
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up-regulation of B-adrenergic receptors
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down-regulation of B-adrenergic receptors
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the therapy should be ceased abruptly
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the therapy should not be ceased abruptly
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