Leucocyte Pathologies

Beschreibung

Haematology and Anatomy (Leukocytes) Quiz am Leucocyte Pathologies, erstellt von gina_evans0312 am 09/01/2014.
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Zusammenfassung der Ressource

Frage 1

Frage
In Flow Cytometry, cell size is measured as they pass through laser beams
Antworten
  • True
  • False

Frage 2

Frage
Why is this area left?
Antworten
  • Excludes cells with low CD45
  • Excludes small cells
  • Excludes cells too large to pass through

Frage 3

Frage
In Flow Cytometry, the Ig tested for varies depending on which cell you're measuring
Antworten
  • True
  • False

Frage 4

Frage
For which cell would you use an alkaline reagent?
Antworten
  • Eosinophils
  • Basophils
  • Monocytes

Frage 5

Frage
Normal range of W.B.C's is 4-11 (x10^7/l)
Antworten
  • True
  • False

Frage 6

Frage
What is to be expected in a Settling test from a leukaemia patient?
Antworten
  • Thinker plasma layer
  • Thicker buffy coat layer
  • Thicker erythrocyte layer

Frage 7

Frage
Why is a strong lysing solution added to a W.B.C count?
Antworten
  • Remove R.B.C's
  • Remove platelets

Frage 8

Frage
Like R.B.C's, W.B.C's are counted using current impedence
Antworten
  • True
  • False

Frage 9

Frage
What are the two populations (peaks) shown here?
Antworten
  • Lymphocytes
  • Monocytes
  • Nutraphils
  • All others

Frage 10

Frage
What two things are mapped in D.I.F.F?
Antworten
  • Size
  • Shape
  • Granularity
  • Markers

Frage 11

Frage
What cells are being pointed at on the graph?
Antworten
  • Netraphils
  • Monocytes
  • Lymphocytes

Frage 12

Frage
Cellpack & Stromatolyers 3D do what?
Antworten
  • Protect W.B.C's
  • Speed R.B.C's lysis

Frage 13

Frage
List some causes of Neutropenia
Antworten
  • Overwhelming bacterial/viral/funal/parasitic infections
  • Anti-cancer drugs
  • Irradiation
  • Aplastic Anaemia

Frage 14

Frage
Chronic infection/inflammation and increased cytokinase can lead to high...
Antworten
  • Monocytes
  • Eosinophils
  • Basophils

Frage 15

Frage
Basophilia is caused by
Antworten
  • Leukaemias
  • Allergic recations

Frage 16

Frage
Eosinophilia is caused by allergic infections, parasitic infections and drug hypersensitivity
Antworten
  • True
  • False

Frage 17

Frage
Name some causes of Lymhpocytopenia
Antworten
  • AIDs
  • Carcinoma
  • Renal failure
  • Vigerous exercise/Smoking

Frage 18

Frage
Name the three tests done for any Leucocytic disorder
Antworten
  • Flow Cytometry
  • Full blood count & DFF
  • NAP test
  • Paul Bunnell Test
  • Morphology

Frage 19

Frage
Why does Clonality indicate a severe pathology?
Antworten
  • A single cell type is proliferating massively
  • Shows a lack of diversity across leucocytes
  • Shows massive infection

Frage 20

Frage
What markers do you test for when looking for Clonality?
Antworten
  • Kappa/lambda markers
  • CD4/CD8
  • Alpha, beta & gamma

Frage 21

Frage
In AIDS, you perform flow cytometry for Kappa/Lambda markers
Antworten
  • True
  • False

Frage 22

Frage
The Paul Bunnel test is done for...
Antworten
  • Viruses
  • Fungi
  • Bacteria

Frage 23

Frage
Name the cause of Haematological Malignancies
Antworten
  • Genetics
  • Drugs
  • Irradiation
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