Quiz
Allgemeine und molekulare Genetik 2
Fragen in diesem Quiz (13)
1What's right: Synthetic lethality ...
- ACombinatorial effects between alleles or substances
- BEffects in synthetic biology
- CAn effect specific to a double mutation (not seen in the singles)
- DAn effect specific to a mutation in combination with a SMI-small molecule inhibitor (not seen by either mutation or SMI alone)
2What's right: Phage lambda lysogen ...
- AC1 represses lambda's lysogenic genes, c2 activates int- and c1 transcription, c3 stabilizes c2
- BC1 represses lambda's lysogenic genes, c2 represses int- and c1 transcription, c3 destabilizes c2
- CC1 represses lambda's lytic genes, c2 activates int- and c1 transcription, c3 stabilizes c2
- DC1 represses lambda's lytic genes, c2 represses int- and c1 transcription, c3 destabilizes c2
3What's right: Bacterial transformation
- AThe mechanism of gram+ and gram- DNA uptake is not related
- BGram- bacteria possess an outer membrane requiring an additional pore for DNA uptake
- CGram+ bacteria possess an outer membrane requiring an additional pore for DNA uptake
- DGram+ and gram- bacteria have a pilus structure, a dsDNA receptor and an inner membrane pore in common
4What's right: Intra- vs extragenic complementation
- AGenetic complementation between mutations in different genes does not require wild type alleles
- BExtragenic complementation is rare and requires mutations in different functional domains
- CIntragenic complementation is rare and depends on the presence of domains that function independently
- DMolecular complementation depends on addition of the wild gene
5What's right: Dominant vs epistatic
- Aa is epistatic to locus b , if the double mutant (a,a/b,b) has the same phenotype as the single mutant (a,a)
- Ba is epistatic to b, means: Pht(a,b)=Pht(a,B) .. (although Pht(A,b)≠Pht(A,B))
- Cdominant : Pht(A,A)=Pht(a,A)
- Ddominant relates alleles of 1 gene, epistatic relates an allele to another gene
- EA is dominant over a: Pht(a,A) = Pht(a,a)
6What's right: gene vs allele
- Aa ncRNA is not encoded by a gene, because it is not translated
- Ba centromere is not a gene, because it is not transcribed
- Ca bacterial cistron is not a gene, because it contains several functional units
- Da gene is a functional unit in the genome, activated by transcription while an allele is a sequence variant of a
gene - Ea bacterial operon is not a gene, because it contains several functional units
7What's right: Falsifyability
- AAccording to Popper’s critical rationalism (P.c.r), a Sc.Hyp can’t be claimed true, without evidence
- BAccording to P.c.r. a single experiment, if well performed, can prove a hypothesis forever
- CAccording to P.c.r. a single experiment, if well performed, can disprove a hypothesis forever
- DAccording to P.c.r. a scientific hypothesis must make a prediction, which can be proven wrong
8What's right: Suppressor mutation
- AA suppressor mutation blocks the expression of another gene
- BA suppressor mutation can’t occur in the same gene
- CA suppressor mutation must occur in tRNA
- DA suppressor blocks the appearance of a mutant phenotype
9What's right: What is the phenotype?
- AMany genes do not cause a phenotype
- BThe phenotype of a given mutation must be detectable under all conditions
- CThe phenotype of a mutation can change according to the situation
- DThe phenotype ist the observable impact of an allele
10Connect the topic with the correct boxes/key words ...
BACTERIAL RECOMBINEERING- AattB/P/L/R
- Btargetted DSB
- CRE enzyme free assembly of bacterial, genome-size DNA
- DEfficient, RE enzyme free transfer of inserts between plasmids
- EInhibition of RecBCD
- FRE enzyme free sub cloning from large inserts
- GRE enzyme free correction of genetic defects in vivo
- HBacterial immune system
- IExo, Beta, Gam
- JEdition through DSB-repair
11Connect the topic with the correct boxes/key words ...
GATEWAY TECHNOLOGY- AattB/P/L/R
- Btargetted DSB
- CRE enzyme free assembly of bacterial, genome-sized DNA
- DEfficient, RE enzyme free transfer of inserts between plasmids
- ERE enzyme free sub cloning from large inserts
- FRE enzyme free correction of genetic defects in vivo
- GBacterial immune system
- HExo, Beta, Gam
- IEditing through DSB-repair
- JCloning from donor to recipient
12Connect the topic with the correct boxes/key words ...
CRISPR- AattB/P/L/R
- Btargetted DSB
- CRE enzyme free assembly of bacterial, genome-size DNA
- DEfficient, RE enzyme free transfer of inserts between plasmids
- EInhibition of RecBCD
- FRE enzyme free subcloning from large inserts
- GRE enzyme free correction of genetic defects in vivo
- HBacterial immune system
- IExo, Beta, Gam
- JEditing through DSB-repair
13Connect the topic with the correct boxes/key words ...
YEAST RECOMBINEERING- AattB/P/L/R
- Btargetted DSB
- CRE enzyme free assembly of bacterial, genome-size DNA
- DEfficient, RE enzyme free transfer of inserts between plasmids
- EInhibition of RecBCD
- FRE enzyme free subcloning from large inserts
- GRE enzyme free correction of genetic defects in vivo
- HBacterial immune system
- IExo, Beta, Gam
- JEditing through DSB-repair
Informationen
- Beschreibung
- Bachelor Mikrobiologie Quiz am Allgemeine und molekulare Genetik 2, erstellt von Anna Ullrich am 15/09/2016.
- Autor
- Anna Ullrich
- Sprache
- Deutsch
- Aufrufe
- 22
- Verlauf
- Erstellt am 15 Sep 2016 · aktualisiert am 24 Sep 2016
- Schlagwörter
- Bewertung
- 5,0 von 5 · 1 Bewertung Bewerte dieses Quiz