Exam 2: Biguanides

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College NUR 325 Mind Map on Exam 2: Biguanides, created by Jasper McClellan on 11/07/2022.
Jasper McClellan
Mind Map by Jasper McClellan, updated more than 1 year ago
Jasper McClellan
Created by Jasper McClellan almost 2 years ago
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Resource summary

Exam 2: Biguanides
  1. Nursing Interventions
    1. Monitor LFTs, BUN, and Cr before starting
      1. Continue yearly monitoring
    2. Pharmacokinetics
      1. Not metabolized; excreted unchanged in urine
      2. Adverse effects
        1. Lactic acidosis
          1. Metallic taste in the mouth
            1. Dehydration
              1. Decreased absorption of B12 and folic acid
                1. Weight loss
                2. Contraindications
                  1. Lactic Acid concern:
                    1. Alcoholism
                      1. Hepatic and renal impairment
                        1. Shock
                          1. Severe infection
                            1. Dehydration
                          2. Drug interactions
                            1. Can cause lactic acidosis
                              1. Contrast dyes
                                1. Stop taking 1-2 days before
                                  1. Monitor BUN and Cr
                                  2. Cimetidine
                                  3. Hypoglycemics
                                  4. Pharmacological action
                                    1. Increases sensitivity of insulin receptions
                                      1. Decreases absorption of glucose from the intestines
                                        1. Decreases synthesis of glucose by the liver
                                        2. Other information
                                          1. Advantages
                                            1. Safe for pregnancy
                                              1. No weight gain
                                                1. No hypoglycemia
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