5638208
Description
Quiz by Daniel Mosele, updated more than 1 year ago
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Created by Daniel Mosele
over 10 years ago
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Question 1
Question
Which of the following is true of both Skeletal and Smooth Muscle
Answer
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Presence of the Neuromuscular Junction
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Phosphorylation of Myosin during the Crossbridge Cycle
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Presence of both Thick and Thin myofilaments
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Presence of Troponin
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Presence of Actin
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Acetylcholine is involved
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Calmodulin Complex
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Crossbridge Cycle triggered by an increase in Intracellular Calcium
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Hormones are involved in the activation
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Noradrenaline is invovled
Question 2
Question
In Comparison to Skeletal Muscle, Cardiac Muscle cells:
Answer
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Have Less Nuclei
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Have More Nuclei
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Have Longer Action Potentials
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Have Shorter Action Potentials
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Involve Phosphorylation of Myosin, instead of altering the shape of troponin and position of tropomyosin to reveal a binding site
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Are More branch-like
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Are More linear
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Have Intercalated Discs
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Do not have Intercalacted Discs
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Contraction is triggered by the release of Intracellular Calcium, not extracellular Calcium
Question 3
Question
[blank_start]A Pacemaker Cell[blank_end] in the Heart releases an Action Potential, these spread across the heart. [blank_start]Purkinje Fibres[blank_end] help enhance the spread of the action potential. When the action potential spreads across the cell membrane of individual cardiacmyocytes they invade [blank_start]T tubules[blank_end] (invaginations in the membrane). These cause the opening of [blank_start]Voltage Calcium Channels[blank_end]. [blank_start]Extracellular Calcium[blank_end] then moves into the cytosol. The presence of [blank_start]Calcium[blank_end] in the cytosol causes further release of [blank_start]calcium from the Sarcoplasmic Reticulum[blank_end]. This phenomenon is termed [blank_start]Calcium Dependent Calcium Release[blank_end]. This results in [blank_start]Systole[blank_end]. Strength/Force of Contraction can be modulated by the concentration of [blank_start]Extracellular Calcium.[blank_end]
Answer
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Pacemaker Cells
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Purkinje Fibres
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Sympathetic Nerves
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Alpha Motor Neurons
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Cardiomyocytes
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Purkinje Fibres
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Pacemaker Cells
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Cardiomyocytes
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Sympathetic Nerves
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Adrenaline
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Extracellular Calcium
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Noradrenaline
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GAP Junctions
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Desmosomes
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T tubules
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D Tubules
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M Tubules
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C Tubules
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S Tubules
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Voltage Gated Calcium Channels
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Voltage Gated Sodium Channels
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Voltage Gated Potassium Channels
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Voltage Gated Chloride Channels
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Ligand Gated Calcium Channels
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Ligand Gated Chloride Channels
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Ligand Gated Potassium Channels
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Ligand Gated Sodium Channels
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Extracellular Calcium
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Extracellular Sodium
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Extracellular Chloride
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Extracellular Potassium
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Intracellular Calcium
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Intracellular Sodium
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Intracellular Chloride
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Intracellular Potassium
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Calcium
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Sodium
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ATP
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Potassium
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Chloride
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Calmodulin
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Acetylcholine
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Noradrenaline
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Calcium from the Sarcoplasmic Reticulum
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Calcium from Vesicles
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Calcium from the Interstitial Space
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Sodium from the Sarcoplasmic Reticulum
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Sodium from Vesicles
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Sodium from the Interstitial Space
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Calcium Dependent Chloride Release
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Calcium Dependent Sodium Release
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Sodium Dependent Calcium Release
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Calcium Dependent Calcium Release
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Chloride Dependent Calcium Release
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Sodium Dependant Potassium Release
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Potassium Dependant Calcium Release
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Systole
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Diastole
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Extracellular Calcium.
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Extracellular Potassium
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Extracellular Chloride
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Extracellular Sodium
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Intracellular Calcium
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Intracellular Potassium
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Intracellular Chloride
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Intracellular Sodium
Question 4
Question
With regards to the Transverse Region of Intercalated Discs, which of the following is false?
Answer
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A: Align with the Z Line
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B: Contain Desmosomes
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C: Aid in Mechanical Cohesion
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D: Rich in GAP Junctions
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E: None of the Above
Question 5
Question
In Smooth Muscle Myosin heads are present along the entire length of the thick filament
Answer
- True
- False
Question 6
Question
Which of the following Statements regarding Smooth Muscle is correct?
Answer
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T Tubules are present
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Sarcoplasmic Reticulum is rudimentary
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Caveoli are present
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Actin filaments are attached to Dense Bodies
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Myosin filaments are attached to Dense Bodies
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Desmin forms a diagonal network across the cell membrane
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When Myosin filaments contract they pul on Dense Bodies, and everything is pulled together
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When Actin filaments contract they pull on Dense Bodies, and everything is pulled together
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All Smooth Muscle most be directly stimulated
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GAP Junctions are present in all smooth muscle tissue
Question 7
Question
Multi-unit Smooth Muscle has
Answer
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Few GAP Junctions
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Many GAP Junctions
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Present in the Large Airways of the Lungs
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Present in the Ciliary Muscle of the Eye
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Present in the Wall of the Uterus
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Present in the Wall of the Jejenum
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Multiple adherence points (Desmosomes)
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Poor response to Stretch
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Discrete points of Innervation
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Direct stimulation only present in a few cells
Question 8
Question
Single Unit Smooth Muscle contraction can be innervated/affected by
Answer
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Hormones
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Neural Input
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pH
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Oxygen Levels
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Body Temperature
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All of the Above
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Hormones and Neural Input Only
Question 9
Question
ATP is essential in Smooth Muscle, but has a different role to that of Skeletal Muscle. ATP is required as a substrate for Myosin Light Chain Kinase in the phosphorylation of Myosin Cross Bridges.
Answer
- True
- False
Question 10
Question
Smooth Muscle, like Skeletal Muscle depends upon the release of Calcium from the Sarcoplasmic Reticulum to initiate the cross bridge cycle.
Answer
- True
- False
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