Pregunta 1
Pregunta
Flow rate is how much [blank_start]urine[blank_end] you are [blank_start]producing[blank_end] per unit of [blank_start]time[blank_end]
Respuesta
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urine
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urea
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time
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distance
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producing
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consuming
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voiding
Pregunta 2
Pregunta
GFR is the amount of [blank_start]fluid[blank_end] going into [blank_start]bowmans capsule[blank_end] per unit of [blank_start]time[blank_end]
Respuesta
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fluid
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blood
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bowmans capsule
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the nephron
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time
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flow
Pregunta 3
Pregunta
what is normal glomerular flow rate?
Respuesta
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100-130ml/min
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500-600ml/min
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200-300ml/min
Pregunta 4
Pregunta
Filtered load is the same as
Pregunta 5
Pregunta
[blank_start]Filtered load[blank_end] / tubular load is the [blank_start]amount of a specific solute[blank_end] ([blank_start]electrolyte, glucose or amino acid[blank_end]) entering [blank_start]bowman's capsule[blank_end].
Respuesta
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Filtered load
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amount of a specific solute
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electrolyte, glucose or amino acid
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electrolyte, carbohydrate or protein
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salt
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bowman's capsule
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the kidney
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the nephron
Pregunta 6
Pregunta
Filtered Load can be calculated from [blank_start]GFR[blank_end] and [blank_start]Plasma concentration of solute[blank_end]
Pregunta 7
Respuesta
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freely filtered
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not metabolised
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not reabsorbed
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not secreted
Pregunta 8
Pregunta
Inulin
The excretion rate = ...
Respuesta
-
excretion rate
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filtration rate
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absorption rate
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consumption rate
Pregunta 9
Respuesta
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freely filtered
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not metabolised
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not reabsorbed
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freely secreted
Pregunta 10
Pregunta
What does clearance less than 125ml/min indicate?
Pregunta 11
Pregunta
What does clearance more than 125ml/min indicate?
Pregunta 12
Pregunta
What can be used to experimentally measure GFR?
Respuesta
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Inulin
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glucose
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PAH
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calcium
Pregunta 13
Pregunta
What is elevated Pcr an indicator of?
Respuesta
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reduced GFR
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increased GFR
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non changing GFR
Pregunta 14
Pregunta
Threshold is....
Respuesta
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appearance of solute in urine before you reach the overall Transport maximum of the kidney
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the plasma concentration at which a substance begins to appear in the urine
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the tiny amount of solute appearing in urine when a single nephron reaches its maximum
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the total transport maximum through out all of the nephrons in the kidney
Pregunta 15
Pregunta
what is transport maximum?
Respuesta
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the total transport maximum through out all of the nephrons in the kidney
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The point at which an amount of solute appears in urine when nephrons reaches its maximum
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the plasma concentration at which a substance begins to appear in the urine
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appearance of solute in urine before you reach the overall threshold of the kidney
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The maximum rate of the solute shuttling done by transporters
Pregunta 16
Pregunta
How can renal function be measured?
Respuesta
-
imaging techniques
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renal clearance
Pregunta 17
Pregunta
The [blank_start]renal[blank_end] clearance value of a certain substance is the [blank_start]volume of plasma[blank_end] which is [blank_start]cleared of this substance[blank_end] by the kidney into urine [blank_start]/ min[blank_end].
Pregunta 18
Pregunta
What do we need to know to measure renal clearance?
Respuesta
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volume of urine / min
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concentration of the substance mg/ml urine
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concentration of the substance mg/ml plasma
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concentration of the substance mg/ml blood
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volume of substrate / min
Pregunta 19
Pregunta
What properties does a substance used in a plasma clearance test have?
Respuesta
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does not enter RBCs
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does not affect normal renal function
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should not be metabolized by the kidney
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should be easily measured in plasma & urine
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should be non toxic
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should be easy to consume
Pregunta 20
Pregunta
What do we use renal clearance for?
Pregunta 21
Pregunta
What is the rate-limiting step in the tubular transport of glucose?
Respuesta
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Na-glucose symport
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glucose uniporter
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glucose reabsorption
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ca- glucose symport
Pregunta 22
Pregunta
The plasma leaving the kidney through the renal veins lacks .....
Pregunta 23
Pregunta
What is creatinine?
Respuesta
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the end product of creatine metabolism
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the end product of creatinine metabolism
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a phospholipid
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dumped into the blood by smooth muscle
Pregunta 24
Pregunta
Creatinine is continuously dumped into the blood by....
Respuesta
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smooth muscle
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skeletal muscle
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cardiac muscle
Pregunta 25
Pregunta
the rate of creatinine appearance in blood is proportional to a person's ....
Respuesta
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muscle mass
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fat mass
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urine excretion
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blood
Pregunta 26
Pregunta
Creatinine is....
Respuesta
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freely filtered
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not reabsorbed
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reabsorbed
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not freely filtered
Pregunta 27
Pregunta
how much creatinine is secreted by the proximal tubule?
Respuesta
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10-20%
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40-50%
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70-80%
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85-100%
Pregunta 28
Pregunta
There is a ______________ between plasma creatinine concentration and GFR.
Respuesta
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inverse correlation
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indirect correlation
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direct relationship
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direct correlation
Pregunta 29
Pregunta
What is the most common method used for routine GFR assessments?
Respuesta
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creatinine clearance
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inulin clearance
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PAH clearance
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Plasma clearance
Pregunta 30
Pregunta
If there are more solutes present than can be transported, the solutes will end up...
Respuesta
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In urine
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Reabsorbed
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In the blood stream
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Excreted in faeces
Pregunta 31
Pregunta
Renal clearance is comparison of [blank_start]filtration[blank_end] rate of a substance to the rate of it's appearance in the [blank_start]urine[blank_end] i.e. Amount [blank_start]filtered[blank_end] vs amount [blank_start]excreted[blank_end]. It gives info on [blank_start]re-absorption[blank_end] and [blank_start]secretion[blank_end]
Respuesta
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filtration
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urine
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urea
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blood
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filtered
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excreted
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re-absorption
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secretion
Pregunta 32
Pregunta
What percentage of clearance?
Respuesta
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A= ?% B=?% C=0% D=100%
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A= 0% B=50% C=0% D=100%
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A= 100% B=0% C=?% D=?%
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A= 25% B=25% C=25% D=25%
Pregunta 33
Pregunta
Renal clearance principle is based on the principle of [blank_start]mass[blank_end] [blank_start]balance[blank_end]. Input of X is [blank_start]equal to[blank_end] output of X
Respuesta
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mass
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balance
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equal to
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more than
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less than
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pressure
Pregunta 34
Pregunta
fill in the formula
Pregunta 35
Pregunta
Tm for PAH secretory mechanism ~80mg/ml.
PPAH [blank_start]<[blank_end] 80mg/ml = good estimation of RPF
PPAH [blank_start]>[blank_end] 80mg/ml = poor estimation of RPF
At [blank_start]low[blank_end] [blank_start]PPAH[blank_end]: [blank_start]PAH[blank_end] clearance [blank_start]=[blank_end] RPF
Pregunta 36
Pregunta
Clearance units are [blank_start]volume[blank_end] per [blank_start]time[blank_end]
Respuesta
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volume
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time
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distance
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meter
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second
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pressure
-
flow
Pregunta 37
Pregunta
Clearance is not the amount of the [blank_start]substance removed[blank_end] but instead the volume of [blank_start]plasma from which it was removed[blank_end].
Pregunta 38
Pregunta
PAH is an abbreviation of ...
Respuesta
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para-aminohippurate
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pilo-acidic-hormone
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pregacilohinutrate
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primary acid hilute