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NAS Basic Processes

H G 5 preguntas Actualizado el 4 abr 2019

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  1. 1The lipid bilayer is a [blank_start]hydrophobic[blank_end] environment. This means that it is [blank_start]impermeable[blank_end] to most molecules including [blank_start]ions[blank_end] (they are usually [blank_start]hydrophilic[blank_end]). This means that intracellular and extracellular compartments are established with very different [blank_start]ionic[blank_end] compositions. Ion [blank_start]pumps[blank_end] are used to [blank_start]maintain[blank_end] the gradient.
    1. Ahydrophobic
    2. Bimpermeable
    3. Chydrophilic
    4. Dions
    5. Epumps
    6. Fmaintain
    7. Gionic
  2. 2The inside of a cell contains a slight excess of [blank_start]anions[blank_end] which sets up a [blank_start]negative[blank_end] voltage inside the cell. This voltage is known as the [blank_start]membrane potential[blank_end] (Em). In neurons this is usually about [blank_start]-65[blank_end]mV. Em is determined by the [blank_start]balance[blank_end] of charges.
    1. Aanions
    2. Bnegative
    3. Cmembrane potential
    4. D-65
    5. Ebalance
  3. 3Ion movement across the membrane is [blank_start]passive[blank_end]. Ion channels are therefore required. There are a few [blank_start]permeant[blank_end] ions (ions that can pass through the channels): Na+, K+, [blank_start]Ca2+[blank_end], Cl-. There are three different types of ion channels that are available:
    Non-gated ([blank_start]leak[blank_end]): these set the [blank_start]Em[blank_end] of the resting membrane
    [blank_start]Voltage[blank_end]: generate the action potential
    [blank_start]Ligand[blank_end] (chemical): generate the Em changes at the [blank_start]synapse[blank_end]
    1. Apassive
    2. Bpermeant
    3. CCa2+
    4. Dleak
    5. EEm
    6. FVoltage
    7. GLigand
    8. Hsynapse
  4. 4The [blank_start]resting membrane potential[blank_end] of the cell is about -65mV. There are several factors that cause this:
    1) the [blank_start]chemical[blank_end] gradient - this is set up due to the [blank_start]potassium[blank_end] [blank_start]efflux[blank_end].
    2) the electrical force - the [blank_start]potassium[blank_end] [blank_start]efflux[blank_end] results in the inside being more [blank_start]negative[blank_end] than the outside. This causes [blank_start]potassium[blank_end] influx. At [blank_start]resting membrane potential[blank_end] there is no net movement of [blank_start]potassium[blank_end].
    3) the [blank_start]permeability[blank_end] of the membrane to each ion - how easy it is for ions to move across the membrane through ion [blank_start]channels[blank_end].
    The following assumptions are made:
    - the membrane is only permeable to [blank_start]potassium[blank_end]
    - the Em is initially [blank_start]0[blank_end]
    1. Aresting membrane potential
    2. Bchemical
    3. Cpotassium
    4. Defflux
    5. Epotassium
    6. Fefflux
    7. Gnegative
    8. Hpotassium
    9. Iresting membrane potential
    10. Jpotassium
    11. Kpermeability
    12. Lchannels
    13. Mpotassium
    14. N0
  5. 5Which of the following is true about the Nernst and Goldman equation?
    1. AThe Nernst equation defines the value at which the potassium ions are just in excess of the sodium ions.
    2. BFor potassium ions, the E(K) value is about -80mV
    3. CFor sodium ions, the E(Na) value is about -62mV
    4. DIf E(m) doesn't equal the E(ion) value, it is due to an imbalance in electrical and chemical effects. This is called to potential driving force.
    5. EThe value of the resting membrane potential is closer to the E(K) value because here the membrane is more permeable to potassium.
    6. FThe Goldman equation is used to calculate the E(m) and where it lies between E(Na) and E(K).

Información

Descripción
Medicine Test sobre NAS Basic Processes, creado por H G el 03/04/2019.
Autor
H G
Idioma
English
Visitas
12
Historial
Creado el 3 abr 2019 · actualizado el 4 abr 2019
Etiquetas
nasmedicine
Valoración
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