DVM1 (Theme 7: Cell Communication - Electrical) Veterinary Bioscience: Cells to Systems Test sobre Lecture 23 Cardiac and Smooth Muscle, creado por Daniel Mosele el 02/06/2016.
Which of the following is true of both Skeletal and Smooth Muscle
Respuesta
Presence of the Neuromuscular Junction
Phosphorylation of Myosin during the Crossbridge Cycle
Presence of both Thick and Thin myofilaments
Presence of Troponin
Presence of Actin
Acetylcholine is involved
Calmodulin Complex
Crossbridge Cycle triggered by an increase in Intracellular Calcium
Hormones are involved in the activation
Noradrenaline is invovled
Pregunta 2
Pregunta
In Comparison to Skeletal Muscle, Cardiac Muscle cells:
Respuesta
Have Less Nuclei
Have More Nuclei
Have Longer Action Potentials
Have Shorter Action Potentials
Involve Phosphorylation of Myosin, instead of altering the shape of troponin and position of tropomyosin to reveal a binding site
Are More branch-like
Are More linear
Have Intercalated Discs
Do not have Intercalacted Discs
Contraction is triggered by the release of Intracellular Calcium, not extracellular Calcium
Pregunta 3
Pregunta
[blank_start]A Pacemaker Cell[blank_end] in the Heart releases an Action Potential, these spread across the heart. [blank_start]Purkinje Fibres[blank_end] help enhance the spread of the action potential. When the action potential spreads across the cell membrane of individual cardiacmyocytes they invade [blank_start]T tubules[blank_end] (invaginations in the membrane). These cause the opening of [blank_start]Voltage Calcium Channels[blank_end]. [blank_start]Extracellular Calcium[blank_end] then moves into the cytosol. The presence of [blank_start]Calcium[blank_end] in the cytosol causes further release of [blank_start]calcium from the Sarcoplasmic Reticulum[blank_end]. This phenomenon is termed [blank_start]Calcium Dependent Calcium Release[blank_end]. This results in [blank_start]Systole[blank_end]. Strength/Force of Contraction can be modulated by the concentration of [blank_start]Extracellular Calcium.[blank_end]
Respuesta
Pacemaker Cells
Purkinje Fibres
Sympathetic Nerves
Alpha Motor Neurons
Cardiomyocytes
Purkinje Fibres
Pacemaker Cells
Cardiomyocytes
Sympathetic Nerves
Adrenaline
Extracellular Calcium
Noradrenaline
GAP Junctions
Desmosomes
T tubules
D Tubules
M Tubules
C Tubules
S Tubules
Voltage Gated Calcium Channels
Voltage Gated Sodium Channels
Voltage Gated Potassium Channels
Voltage Gated Chloride Channels
Ligand Gated Calcium Channels
Ligand Gated Chloride Channels
Ligand Gated Potassium Channels
Ligand Gated Sodium Channels
Extracellular Calcium
Extracellular Sodium
Extracellular Chloride
Extracellular Potassium
Intracellular Calcium
Intracellular Sodium
Intracellular Chloride
Intracellular Potassium
Calcium
Sodium
ATP
Potassium
Chloride
Calmodulin
Acetylcholine
Noradrenaline
Calcium from the Sarcoplasmic Reticulum
Calcium from Vesicles
Calcium from the Interstitial Space
Sodium from the Sarcoplasmic Reticulum
Sodium from Vesicles
Sodium from the Interstitial Space
Calcium Dependent Chloride Release
Calcium Dependent Sodium Release
Sodium Dependent Calcium Release
Calcium Dependent Calcium Release
Chloride Dependent Calcium Release
Sodium Dependant Potassium Release
Potassium Dependant Calcium Release
Systole
Diastole
Extracellular Calcium.
Extracellular Potassium
Extracellular Chloride
Extracellular Sodium
Intracellular Calcium
Intracellular Potassium
Intracellular Chloride
Intracellular Sodium
Pregunta 4
Pregunta
With regards to the Transverse Region of Intercalated Discs, which of the following is false?
Respuesta
A: Align with the Z Line
B: Contain Desmosomes
C: Aid in Mechanical Cohesion
D: Rich in GAP Junctions
E: None of the Above
Pregunta 5
Pregunta
In Smooth Muscle Myosin heads are present along the entire length of the thick filament
Respuesta
True
False
Pregunta 6
Pregunta
Which of the following Statements regarding Smooth Muscle is correct?
Respuesta
T Tubules are present
Sarcoplasmic Reticulum is rudimentary
Caveoli are present
Actin filaments are attached to Dense Bodies
Myosin filaments are attached to Dense Bodies
Desmin forms a diagonal network across the cell membrane
When Myosin filaments contract they pul on Dense Bodies, and everything is pulled together
When Actin filaments contract they pull on Dense Bodies, and everything is pulled together
All Smooth Muscle most be directly stimulated
GAP Junctions are present in all smooth muscle tissue
Pregunta 7
Pregunta
Multi-unit Smooth Muscle has
Respuesta
Few GAP Junctions
Many GAP Junctions
Present in the Large Airways of the Lungs
Present in the Ciliary Muscle of the Eye
Present in the Wall of the Uterus
Present in the Wall of the Jejenum
Multiple adherence points (Desmosomes)
Poor response to Stretch
Discrete points of Innervation
Direct stimulation only present in a few cells
Pregunta 8
Pregunta
Single Unit Smooth Muscle contraction can be innervated/affected by
Respuesta
Hormones
Neural Input
pH
Oxygen Levels
Body Temperature
All of the Above
Hormones and Neural Input Only
Pregunta 9
Pregunta
ATP is essential in Smooth Muscle, but has a different role to that of Skeletal Muscle. ATP is required as a substrate for Myosin Light Chain Kinase in the phosphorylation of Myosin Cross Bridges.
Respuesta
True
False
Pregunta 10
Pregunta
Smooth Muscle, like Skeletal Muscle depends upon the release of Calcium from the Sarcoplasmic Reticulum to initiate the cross bridge cycle.