Lecture 23 Cardiac and Smooth Muscle

Descripción

DVM1 (Theme 7: Cell Communication - Electrical) Veterinary Bioscience: Cells to Systems Test sobre Lecture 23 Cardiac and Smooth Muscle, creado por Daniel Mosele el 02/06/2016.
Daniel Mosele
Test por Daniel Mosele, actualizado hace más de 1 año
Daniel Mosele
Creado por Daniel Mosele hace más de 10 años
7
1

Resumen del Recurso

Pregunta 1

Pregunta
Which of the following is true of both Skeletal and Smooth Muscle
Respuesta
  • Presence of the Neuromuscular Junction
  • Phosphorylation of Myosin during the Crossbridge Cycle
  • Presence of both Thick and Thin myofilaments
  • Presence of Troponin
  • Presence of Actin
  • Acetylcholine is involved
  • Calmodulin Complex
  • Crossbridge Cycle triggered by an increase in Intracellular Calcium
  • Hormones are involved in the activation
  • Noradrenaline is invovled

Pregunta 2

Pregunta
In Comparison to Skeletal Muscle, Cardiac Muscle cells:
Respuesta
  • Have Less Nuclei
  • Have More Nuclei
  • Have Longer Action Potentials
  • Have Shorter Action Potentials
  • Involve Phosphorylation of Myosin, instead of altering the shape of troponin and position of tropomyosin to reveal a binding site
  • Are More branch-like
  • Are More linear
  • Have Intercalated Discs
  • Do not have Intercalacted Discs
  • Contraction is triggered by the release of Intracellular Calcium, not extracellular Calcium

Pregunta 3

Pregunta
[blank_start]A Pacemaker Cell[blank_end] in the Heart releases an Action Potential, these spread across the heart. [blank_start]Purkinje Fibres[blank_end] help enhance the spread of the action potential. When the action potential spreads across the cell membrane of individual cardiacmyocytes they invade [blank_start]T tubules[blank_end] (invaginations in the membrane). These cause the opening of [blank_start]Voltage Calcium Channels[blank_end]. [blank_start]Extracellular Calcium[blank_end] then moves into the cytosol. The presence of [blank_start]Calcium[blank_end] in the cytosol causes further release of [blank_start]calcium from the Sarcoplasmic Reticulum[blank_end]. This phenomenon is termed [blank_start]Calcium Dependent Calcium Release[blank_end]. This results in [blank_start]Systole[blank_end]. Strength/Force of Contraction can be modulated by the concentration of [blank_start]Extracellular Calcium.[blank_end]
Respuesta
  • Pacemaker Cells
  • Purkinje Fibres
  • Sympathetic Nerves
  • Alpha Motor Neurons
  • Cardiomyocytes
  • Purkinje Fibres
  • Pacemaker Cells
  • Cardiomyocytes
  • Sympathetic Nerves
  • Adrenaline
  • Extracellular Calcium
  • Noradrenaline
  • GAP Junctions
  • Desmosomes
  • T tubules
  • D Tubules
  • M Tubules
  • C Tubules
  • S Tubules
  • Voltage Gated Calcium Channels
  • Voltage Gated Sodium Channels
  • Voltage Gated Potassium Channels
  • Voltage Gated Chloride Channels
  • Ligand Gated Calcium Channels
  • Ligand Gated Chloride Channels
  • Ligand Gated Potassium Channels
  • Ligand Gated Sodium Channels
  • Extracellular Calcium
  • Extracellular Sodium
  • Extracellular Chloride
  • Extracellular Potassium
  • Intracellular Calcium
  • Intracellular Sodium
  • Intracellular Chloride
  • Intracellular Potassium
  • Calcium
  • Sodium
  • ATP
  • Potassium
  • Chloride
  • Calmodulin
  • Acetylcholine
  • Noradrenaline
  • Calcium from the Sarcoplasmic Reticulum
  • Calcium from Vesicles
  • Calcium from the Interstitial Space
  • Sodium from the Sarcoplasmic Reticulum
  • Sodium from Vesicles
  • Sodium from the Interstitial Space
  • Calcium Dependent Chloride Release
  • Calcium Dependent Sodium Release
  • Sodium Dependent Calcium Release
  • Calcium Dependent Calcium Release
  • Chloride Dependent Calcium Release
  • Sodium Dependant Potassium Release
  • Potassium Dependant Calcium Release
  • Systole
  • Diastole
  • Extracellular Calcium.
  • Extracellular Potassium
  • Extracellular Chloride
  • Extracellular Sodium
  • Intracellular Calcium
  • Intracellular Potassium
  • Intracellular Chloride
  • Intracellular Sodium

Pregunta 4

Pregunta
With regards to the Transverse Region of Intercalated Discs, which of the following is false?
Respuesta
  • A: Align with the Z Line
  • B: Contain Desmosomes
  • C: Aid in Mechanical Cohesion
  • D: Rich in GAP Junctions
  • E: None of the Above

Pregunta 5

Pregunta
In Smooth Muscle Myosin heads are present along the entire length of the thick filament
Respuesta
  • True
  • False

Pregunta 6

Pregunta
Which of the following Statements regarding Smooth Muscle is correct?
Respuesta
  • T Tubules are present
  • Sarcoplasmic Reticulum is rudimentary
  • Caveoli are present
  • Actin filaments are attached to Dense Bodies
  • Myosin filaments are attached to Dense Bodies
  • Desmin forms a diagonal network across the cell membrane
  • When Myosin filaments contract they pul on Dense Bodies, and everything is pulled together
  • When Actin filaments contract they pull on Dense Bodies, and everything is pulled together
  • All Smooth Muscle most be directly stimulated
  • GAP Junctions are present in all smooth muscle tissue

Pregunta 7

Pregunta
Multi-unit Smooth Muscle has
Respuesta
  • Few GAP Junctions
  • Many GAP Junctions
  • Present in the Large Airways of the Lungs
  • Present in the Ciliary Muscle of the Eye
  • Present in the Wall of the Uterus
  • Present in the Wall of the Jejenum
  • Multiple adherence points (Desmosomes)
  • Poor response to Stretch
  • Discrete points of Innervation
  • Direct stimulation only present in a few cells

Pregunta 8

Pregunta
Single Unit Smooth Muscle contraction can be innervated/affected by
Respuesta
  • Hormones
  • Neural Input
  • pH
  • Oxygen Levels
  • Body Temperature
  • All of the Above
  • Hormones and Neural Input Only

Pregunta 9

Pregunta
ATP is essential in Smooth Muscle, but has a different role to that of Skeletal Muscle. ATP is required as a substrate for Myosin Light Chain Kinase in the phosphorylation of Myosin Cross Bridges.
Respuesta
  • True
  • False

Pregunta 10

Pregunta
Smooth Muscle, like Skeletal Muscle depends upon the release of Calcium from the Sarcoplasmic Reticulum to initiate the cross bridge cycle.
Respuesta
  • True
  • False
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