6308561
Descripción
Test por Jim Shimoda, actualizado hace más de 1 año
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Creado por Jim Shimoda
hace más de 7 años
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Pregunta 1
Pregunta
Congenital adrenal hyperplasia can be caused by...
Respuesta
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A lack of 21-Beta-Hydroxylase
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A lack of 11-alpha-hydroxylase
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A lack of both
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A lack of either
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None of the above
Pregunta 2
Pregunta
A lack of oxytocin can be caused by
Respuesta
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A problem with the anterior pituitary gland
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A problem with the supraoptic nucleus of the hypothalamus
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An excess of vasopressin
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Grave's disease
Pregunta 3
Pregunta
Oxytocin and vasopressin are protected from degradation by
Respuesta
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Antigens
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Their large size
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Amidation
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Disulfide bridges
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Both amidation and disulfide bridges
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Amidation and antigens
Pregunta 4
Pregunta
A patient presents with moon facies, abdominal striations, a hump behind the neck, and abdominal adipose tissue build up, tests demonstrate high cortisol and high ACTH levels. This patient most likely has:
Respuesta
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Addison's disease
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Cushing's Syndrome caused by adrenal malfunction
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Cushing's Syndrome caused by Cushing's disease
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Wollf-Chaikov disease
Pregunta 5
Pregunta
Which of these is the strongest inhibitor of ACTH production?
Respuesta
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High cortisol levels
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Sleep-wake transition
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High Growth Hormone levels
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Hyperthyroidism
Pregunta 6
Pregunta
A lack of Tyrosine in the thyroid would cause
Respuesta
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The overproduction of T4
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The underproduction of T3
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The overproduction of TBG
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The underproduction of both T3 and T4
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The underproduction of both TBG and TSH
Pregunta 7
Pregunta
Competitive inhibition of the follicular iodide pump due to excess _____________ can halt the production of ___________
Respuesta
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perchlorate ; thyroid hormones
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thyroid hormones ; TSH
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TSH ; thyroid hormones
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Oxytocin ; Vasopressin
Pregunta 8
Pregunta
(Choose the most accurate answer) - Synthesis of Thyroid hormones (T3 and T4) occurs....
Respuesta
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In the pituitary gland
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In the thyroid
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In the follicular space
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In the follicular cells
Pregunta 9
Pregunta
A patient in the first trimester of pregnancy presents with hyperthyroidism, high Thyroid hormone levels, and low TSH levels. The recommended course of treatment is
Respuesta
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PTU
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Methimazole
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Exogenous TSH
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Radioactive Iodine
Pregunta 10
Pregunta
Prenatal iodine deficiency causes
Respuesta
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Cretinism
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Overproduction of Growth Hormone
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Grave's disease
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Hashimoto's Thyroiditis
Pregunta 11
Pregunta
________ has a longer half-life in plasma
Respuesta
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T4
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T3
Pregunta 12
Pregunta
Conversion of T4 to T3 occurs in the:
Respuesta
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Thyroid
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Pituitary gland
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Peripheral tissues
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TBG
Pregunta 13
Pregunta
Choose the correct relationship between somatostatin and the hormone(s) below:
Respuesta
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Somatostatin inhibits TSH, Promotes GH
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Somatostatin inhibits both TSH and GH
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Somatostatin inhibits GH, has no effect on TSH
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Somatostatin promotes TSH and inhibits GH
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Somatostatin has no effect on TSH or GH
Pregunta 14
Pregunta
Thyroid hormone receptors are:
Respuesta
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Bound to DNA and activated when T3 binds to the receptor
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In the nucleus, are activated and bind to DNA when T3 binds the receptor
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On the membrane of cells, act via second messengers
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Deactivated by HSP90 binding, which is only removed when T3 binds the receptor
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Only activated by T4, not T3
Pregunta 15
Pregunta
Hashimoto's thyroiditis is causes
Respuesta
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Hyperthyroidism
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Hypothyroidism
Pregunta 16
Pregunta
Cerebral osmoreceptors in the __________ respond to changes in the blood osmolality
Respuesta
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Supraoptic nucleus
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OVLT and SFO
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Posterior pituitary
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Anterior pituitary
Pregunta 17
Pregunta
Plasma concentration of AVP is a function of....
Respuesta
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ADH concentration
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Osmotic threshold
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Oxytocin concentration
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Urine osmolality and Osmotic Threshold
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Plasma osmolality and Osmotic Threshold
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Plasma Osmolality, osmotic threshold, and BP
Pregunta 18
Pregunta
Maximum antidiuresis occurs at what concentration of AVP?
Respuesta
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5 pg/ml
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20 pg/ml
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5 mg/ml
Pregunta 19
Pregunta
At constant plasma osmolality, a decrease in blood pressure leads to
Respuesta
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An increase of AVP concentration
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An increase of oxytocin concentration
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A decrease of AVP concentration
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Both A and B
Pregunta 20
Pregunta
AVP functions by
Respuesta
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Increasing the number of Aquaporins in the kidney tubule lumen
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increasing Protein Kinase A activity in kidney tubule cells
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Exocytosis of AQP2 containing vesicles in kidney tubule cells
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All of the above
Pregunta 21
Pregunta
Nephrogenic diabetes insipidus is caused by:
Respuesta
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Lack of AVP production in the posterior pituitary
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Problems with V1a receptors in the CNS
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Problems with V2 receptors in the kidneys
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Problems with oxytocin receptors
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Placental secretion of vasopressinase
Pregunta 22
Pregunta
If excess Potassium is detected, ____________ secretion will occur
Respuesta
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Aldosterone
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Cortisol
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Growth Hormone
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Vasopressin
Pregunta 23
Pregunta
Steroid receptors work by
Respuesta
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Binding HSP90 and beginning transcription
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Binding G-proteins that have been released by membrane receptors
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Releasing HSP90 upon binding a steroid
Pregunta 24
Pregunta
What is the major dimerization partner for receptors?
Respuesta
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RAR
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RXR
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PPAR
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GR
Pregunta 25
Pregunta
In a Stachard plot, a hormone that binds two different receptors with different affinities makes a _________ line.
Respuesta
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Straight
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Curved
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It actually makes two lines
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Vetical
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Horizontal
Pregunta 26
Pregunta
On a hormone binding curve, a left-shift equals a(n) ___________
Respuesta
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Increase in affinity
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Decrease in affinity
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increase in plasma hormone concentration
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Decrease in plasma hormone concentration
Pregunta 27
Pregunta
In the islet of Langerhans
Respuesta
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Beta cells produce glucagon
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Gamma cells produce insulin
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Blood flows from the periphery to the center
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Beta cells are the most numerous
Pregunta 28
Pregunta
In the pancreas, endocrine glands secret ___________ and exocrine glands secrete ___________
Respuesta
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directly into an artery ; directly into a vein
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into a vein ; into the digestive system
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into the pancreatic duct ; into the venous system
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into the digestive system ; into the liver
Pregunta 29
Pregunta
The cell type(s) of the islet of langerhans that serete Ghrelin are:
Respuesta
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Epsilon and alpha
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Beta and alpha
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F cells
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Beta only
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epsilon only
Pregunta 30
Pregunta
Pancreatic F cells release:
Respuesta
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Insulin
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Glucagon
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Somatostatin
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Pancreatic polypeptide
Pregunta 31
Pregunta
Put these steps into the proper order for Insulin excretion
1) Rise in ATP
2) Opening of inflowing calcium channels
3) Entry of Glucose through the GLUT2 channel
4)Opening of Voltage gated K channel
5) Insulin secretion
Respuesta
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1, 5, 3, 4, 2
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3, 1, 5, 2, 4
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4, 3, 1, 2, 5
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3, 1, 4, 2, 5
Pregunta 32
Pregunta
Insulin exocytosis from Beta cells is most similar to which process:
Respuesta
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TBG exocytosis from the thyroid follicle cells
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Exocrine gland function of pancreas cells
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Acetylcholine exocytosis in the Neuromuscular junction
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Posterior pituitary hormone release
Pregunta 33
Pregunta
In the presence of high norepinephrine levels, the exocytosis of insulin from Beta cells is
Respuesta
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Increased
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Inhibited
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Unaffected
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Only affected if epinephrine is also present
Pregunta 34
Pregunta
How does amylin assist in glycemic regulation
Respuesta
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It doesn't
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Slows gastric emptying
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Boosts insulin levels
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Forms plaques that speed glucose uptake
Pregunta 35
Pregunta
How does caffeine effect Beta cell exhaustion
Respuesta
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Dude, caffeine is bad for you. Everyone knows that.
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Breaks up amyloid plaques, keeping Beta cells functional longer
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Slows insulin release, regulating Beta cell function
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Stimulates insulin release, helping relieve type 2 diabetes
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Stimulates insulin release, helping relieve type 1 diabetes
Pregunta 36
Pregunta
Over-release of growth hormone in childhood causes:
Respuesta
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Gigantism
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Acromegaly
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TSH release
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Glucocorticoid release
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