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Physiology of Aging: Theories, VO2max and Muscle Decline

Joseph Kinder Inglés 33 fichas

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  1. 1PathologericThis is considered pathological; not a predestined part of aging
  2. 225-30 yearsThis is the age at which most physiological declines begin
  3. 3Rate of Living TheoryTheory that states that the faster an organism's metabolism, the shorter its lifespan
  4. 4Accumulation TheoryTheory suggests a functional decline w/ aging resulting from the accumulation of biproducts from cellular metabolism
  5. 570 yearsThe age at which a decrease in weight tends to occur
  6. 6DeclinesThis is what happens to RMR w/ older age
  7. 7go down/declineLoss in muscle mass causes RMR to do this
  8. 8Disease BurdenHigher RMR in older sedentary adults is indicative of this
  9. 9Oxidative StressThis may result from chronic elevations in oxidative/aerobic metabolism
  10. 10SOD, GPX, catalaseThis is an example of an endogenous antioxidant
  11. 115% per decadeThe rate in decline of VO2max that occurs with older age in highly active individuals
  12. 12Walking/Exercise EconomyThe measure of the amount of energy required (metabolic cost) to travel 1.5 mph
  13. 13AerobicReliance on this energy system predominates w/ older age
  14. 14SDHThe activity of this metabolic enzyme improves w/ AEX even in older adults
  15. 15ReducedWhat happens to muscle glycogen levels with older age
  16. 1610%The % decline in muscle mass that occurs by 50 years old in inactive individuals
  17. 17Type IOlder age results in greater shift to this fiber type
  18. 18Low Muscle QualityInfiltration of IMAT results in this
  19. 1960-80 yearsMajor decrements in muscle fiber size occur within this age range
  20. 20Loss of alpha motor unitsloss of total muscle fibers that occurs w/ older age is closely related to this
  21. 21FNIHDefinition of sarcopenia that includes ALM/BMI and low muscle strength
  22. 22SPPBThis test for physical function includes balance, gait speed and chair stand
  23. 230.3 W/kgThe minimum muscle power needed to rise from a chair
  24. 24greater or equal to 15sThe time in four-square step test that is indicative of greater disability
  25. 25<20kgAccording to the EWGSOP, this is the cutoff for handgrip strength in women
  26. 26Skeletal Muscle CapillariesThis is necessary for adequate perfusion of skeletal muscle
  27. 27greater than or equal to 12sThis time in the TUG test is indicative of greater fall risk
  28. 28CalciumThis mineral adds strength to the bone and hardens the framework
  29. 29RigidityThis feature of bone that allows for movement
  30. 30Onset of symptoms occurs ~10 years earlier in this type of arthritisp
  31. 31OsteoclastsThese cells break down and remove old/damaged bone
  32. 32below -2.5The T-score associated w/ osteoporosis
  33. 33Weight bearing (high loading)What type of exercise is best for improving BMD?

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Fichas sobre Sin título, creado por Joseph Kinder el 28/03/2023.
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