Histamine & Histaminergic Receptors

Pregunta	Respuesta
Source of Histamine	Histadine
Sources of Histamine	Red granules of Mast cells, or Endochromaffin cells/histaminergic neurons
No of Histaminergic receptors	4
Receptors worked on by anti-histaminics	1 & 2
Receptors found on immune cells	1, 2 & 4
H1- Location	Smooth muscle of the respiratory tract & on vascular endothelial cells
H1- Role	Sooth Muscle contraction, vasodilation and immune modulation
H1- Effects	Breathless/wheezing & redness/itching
H2- Location	Gastroparietal & heart cells
H2- Effects	Inc. acid production & inc heart contraction
H3- Location	Part of the CNS
H3- Role	Sleep cycle & cognition
Histamine receptors are _ coupled	G-protein
Net result of histamine receptor stimulation	Inc Ca2+, Adenylate Cyclase and MAPK stimulation

Resumen del Recurso

	Creado por gina_evans0312 hace alrededor de 10 años