Dispepsia and Acid Secretion

gina_evans0312
Flashcards by gina_evans0312, updated more than 1 year ago
gina_evans0312
Created by gina_evans0312 about 7 years ago
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Year 2 Flashcards on Dispepsia and Acid Secretion, created by gina_evans0312 on 02/06/2014.

Resource summary

Question Answer
Dispepsia symptoms Range of symptoms- abdominal pain, heartburn, nausia
Functional Dispepsia Where there's no physical cause
Gastritis Inflammation of the stomach lining
Peptic Ulcers In stomach/on duodenum where acid has eaten through
Malignancy Rare but possible cause of dispepsia
Mucus Neck Cells Found in 'stomach pits' and secrete mucus for acid protection
Mucus on Stomach Lining Works by neutralizing acid
Gastro-Parietal Cell Produce stomach acid using a proton/potassium pump
H+/K+ Pump Activation By H2 receptors through 3,5-cAMP
Enterochromaffin Cells Produce the histamine that stimulates the H2 receptor
Inhibiting Acid Production Anti-histaminics or proton pump inhibitors (more effective)
Risk factors for peptic ulcers Prolonged NSAID use or Helicobacter Pylori bacteria
Helicobacter Pylori Causes inflammation by penetrating mucus barrier and depleting it
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