Dispepsia and Acid Secretion

Question	Answer
Dispepsia symptoms	Range of symptoms- abdominal pain, heartburn, nausia
Functional Dispepsia	Where there's no physical cause
Gastritis	Inflammation of the stomach lining
Peptic Ulcers	In stomach/on duodenum where acid has eaten through
Malignancy	Rare but possible cause of dispepsia
Mucus Neck Cells	Found in 'stomach pits' and secrete mucus for acid protection
Mucus on Stomach Lining	Works by neutralizing acid
Gastro-Parietal Cell	Produce stomach acid using a proton/potassium pump
H+/K+ Pump Activation	By H2 receptors through 3,5-cAMP
Enterochromaffin Cells	Produce the histamine that stimulates the H2 receptor
Inhibiting Acid Production	Anti-histaminics or proton pump inhibitors (more effective)
Risk factors for peptic ulcers	Prolonged NSAID use or Helicobacter Pylori bacteria
Helicobacter Pylori	Causes inflammation by penetrating mucus barrier and depleting it

Resource summary

	Created by gina_evans0312 about 10 years ago