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Nerves Hormones and Target Tissue

Alannah Kelly Reproduction - Nerves Hormones and Target Tissue University Inglés 18 fichas

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  1. 1Highlight the difference between a simple neural reflex and neuroendocrine reflex.Simple: employs nerves that release their neurotransmitters directly onto target tissue.
    Neuroendocrine: requires that a neurohormone enters the blood and acts on the remote target tissue.
  2. 2What Hormones does the hypothalamic nuclei produce?GnRH and Oxytocin.
  3. 3How does the paraventricular nucleus and surge/tonic centres communicate with the posterior and anterior pituitary respectively?anterior: a special circulatory modification called the hypothalamo-hypophyseal portal system.
    posterior: neurons are deposited directly into capillaries in the posterior pituitary.
  4. 4Classify reproductive hormones by their glandular origin.Hypothalamus
    Pituitary
    Gonads
    Uterus
    Placenta
  5. 5What hormones does the hypothalamus produce?GnRH
    Gonadotropin releasing hormone
  6. 6What hormones does the pituitary produce?FSH: follicle stimulating hormone
    LH: luteinizing hormone
    Oxytocin
  7. 7What hormones do the gonads produce?In the ovary: estrogens, progesterones, inhibin, some testosterone, oxytocin and relaxin.
    In the testes: testosterone and other androgens, inhibin and some estrogens.
  8. 8What hormones are produces in the uterus and placenta?Uterus: prostaglandin F (PGF)
    Placenta: progesterone, estrogen, equine chorionic gonadotrophin (eCG) and human chorionic gonadotrophin (hCG)
  9. 9Classify reproductive hormones by their mode of action.Neurohormones
    Releasing hormones
    Gonadotrophins
    Sexual Promoters
    Maintenance of Pregnancy
    Luteolytic
  10. 10Classify reproductive hormones by their biochemical structure.Proteins
    Inhibin and activin
    steroids
    prostaglandins
  11. 11The strength of hormone action is influenced by:The pattern and duration of secretion.
    The half-life of the hormone.
    The density of the receptors on the target organ.
    Receptor-Hormone affinity.
  12. 12Define Agonists:Analogs (having similar chemical structures) that bind to receptors and initially cause the same biological effect as the hormone. Some artificial hormones are more efficient than the native hormones.
  13. 13Define Antagonistsgreater affinity for the hormone receptor but promote weaker biological activity by blocking receptors.
  14. 14How are steroid and protein reproductive hormones metabolised by the liver and excreted in the urine and faeces?1. Steroid secreted by gonads.
    2. Steroid enters blood and goes to target tissue.
    3. Steroid causes change in target tissue.
    4. Steroid in blood passes through the liver.
    5. Liver renders steroid H2O soluble.
    6. Reenters blood and kidney or enters bile.
    7. Excreted in urine and/or faeces as glucuronide or sulfate.
  15. 15What are the practical implications of being able to measure hormones in urine, faeces and saliva?-non invasive but you are measuring hormone metabolites not the biological active hormone.
    - a lot of work and theres a lag phase.
  16. 16What are the typical patterns of hormonal secretion by the reproductive system and give an example of each?Episodic: usually hormones under direct nervous control (GnRH, LH and T)
    Basal or tonic: low but fluctuates with low amplitude pulses (FSH)
    Sustained: hormone remains elevated but secreted in a stable stead state (Progesterone)
  17. 17Define Up-regulation:Receptor density is elevated.
  18. 18Define Down-Regulation:Reduced receptor density.

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Animal Reproduction - the regulation of nerves, hormones and target tissues
Creado por
Alannah Kelly
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