¡GoConqr estrena diseño! Cuéntanos qué te parece.

Fichas

Vector

tate0295 Medical Parasitology MSc Inglés 54 fichas

Vector

Fichas del conjunto (54)

  1. 1Extrinsic incubation Period (EIP)Time to infectioness in vector
  2. 2Biological vectorsCarry paths that multiply within vector and are transmitted usually by biting
  3. 3Mechanical vectorsPick up paths externally and transmit by physical contact; Often require interrupted feeding or short time between moving from source of infection to place of transmission
  4. 4Type I peritrophic matrixStomach is a chitinous sack around blood meal in the mid-gut
  5. 5Type II peritrophic matrixA continuous secreted tube through the midgut
  6. 6Coxal fluidSecreted by ticks during biting; carries paths
  7. 7Vector manipulation during infectiousnessProbing behaviour of infected mosquitoes altered; Lower [apyrase] in saliva = increased clotting in host; means more probing required to feed = greater chance of transmission, esp. if seeking another host to complete blood meal
  8. 8Mosquito borne diseaseMosquito borne disease
  9. 9Mosquito matingAdult female mates soon after emergence - swarming; sperm stored in spermathecae to fertilise multiple batches of eggs; Anopheles males may insert plug into female to prevent further mating
  10. 10Anopheline larval morphologyNo siphon - lie flat at water surface
  11. 11Stegomyia larval morphologyShorter, darker siphon, with one pair of sub-ventral tufts
  12. 12Culex larval morphologyLonger, narrow siphon, with more than one pair of sub-ventral tufts
  13. 13Mosquito pupal morphologyVery similar between sub-genera; swim but don't feed; identification mainly by rearing to adults
  14. 14Anopheles adultsHead down, body up when feeding; Long palps with white banding; Male palps are club shaped
  15. 15Culicine adultsHead down, body level when feeding; Short palps; Male palps not club shaped
  16. 16Temperature dependency for mosquito egg developmentDays in the topics; Weeks in temperate/arctic environments
  17. 17Anopheles breeding and egg layingTypically found in open, sunlit water; Single eggs with floats; Dislike concrete &/or organic pollution in breeding sites, overgrown with vegetation; LIKE temporary, small pools of water - e.g. hoof prints after rains, flooded cultivation ridges; However, An. funestus prefer dense vegetation
  18. 18Anopheles culcifacesMain vector in rural India and Sri Lanka; Occupies pools of stagnant water by streams/rivers - peak in dry season as water levels fall; Density dependent transmission - at low density, mainly zoophagic, so low transmission; Endophilic to easy to target with IRS
  19. 19Anopheles stephensiMain urban vector in India; Breeds in large man-made containers, e.g. water tanks;
  20. 20Anopheles dirusMajor malaria vector in forests of SE Asia; Breeds in shaded pools; Highly efficient vector of MDR Plasmodium; Loggers and hunters at risk
  21. 21Anopheles albimanusMalaria vector in S America; Breeds in water bodies broken with leaves of flotage; Active at night but may feed during the day; Weight of numbers vector; In dry season, can breed in brackish coastal lagoons
  22. 22Anopheles darlingiMajor malaria vector in Amazon; Habitats created by deforestation; streams, puddles, ponds
  23. 23i lovepal
  24. 24Larval dippingWith ladle; larval numbers per dip is a reliable measure of larval density and how well control is performing
  25. 25Human landing catchUsed to monitor number of bites per person, per day
  26. 26CDC Light TrapsBattery operated light lure; beside a bednet 1m above the ground; catches are proportional to human landing catch; Preferable method
  27. 27Pyrethrum spray collectionsCover all surfaces inside with sheets; Spray indoors to knock down mosquitoes for collection - good condition for dissection
  28. 28Exit trap collectionTo catch mosquitoes exiting from windows during the night; Mosquitoes that bite indoors but then rest outside are caught - invulnerable to IRS
  29. 29Pit trap collectionPit with side tunnels dug to trap outdoor resting Anopheles
  30. 30Animal baited trapsAnimal under a net; to catch zoophagic Anopheles
  31. 31Bednet collectionsSearching for mosquitoes resting indoors in the morning with a torch and pooter; only effective where the nets are untreated
  32. 32Measuring adult survivalPolovodova method - measuring dilations of ovaries; indicative of the number of times a femal has blood fed and become gravid; the older the female, the more likely to be infective
  33. 33Horses for coursesThe choice of vector control methods depends on the setting - ecology, epidemiology, programmatic conditions
  34. 34Adult vector controlMost important, as has disproportionally large effect on vector potential (R0 and C - survival); IRS, ITN/LLIN - standardised, no need for adaption; Robust and broadly efective
  35. 35Larval vector controlAffects density only; Have to target most significant vector; Only if breeding sites are FIXED, FEW & FINDABLE; Must be closely adapted to local conditions
  36. 36Vectorial capacity, CDaily rate of infectious bites per person; Most influenced by survival probability
  37. 37Sporozoite rateThe percentage of females that bear sporozoites in their salivary glands; Expressed as a percentage
  38. 38Pare-Taveta Scheme Intervention1954-1959; effect of IRS on malaria transmission; Massive fall in infant infection, but did not quite reach 0, so deemed a failure
  39. 39Increasing insecticide resistance and reduced developmentResistance is increasing, but new active compounds are not being developed; Mostly for agriculture, which is not safe for IRS; Pyrethroids (1970s) are still the best option
  40. 40Attacking adult vectors with ITNsInsecticide can restore effectiveness of a net with holes; Gives 2x protection vs untreated; Easier - much less insecticide (than IRS), less training, less often; Also contribute to mass effect protection
  41. 41Long lasting insecticides for netsCompounds can now last longer than the lifetime of the net; Can be applied as a coating or incorporated into material; Selling as second hand - can people tell if they are (still) treated?
  42. 42ITNs and child mortalityEven where children do not develop immunity due to exposure, there is no rebound in mortality, as long as net usage remains; However, younger children are more likely to be covered than older children
  43. 43ITN/LLIN vs IRSSimilar impacts on malaria; LLIN longer lasting, less logistically challenging; IRS campaigns can fail unless well planned and implemented - nets can be simply given out; IRS needs to occur once or twice per year - LLINs may last 3 years
  44. 44Choosing ITN/LLIN or IRSBased on feasibility and sustainability on large scale; IRS advantages against highly seasonal, unstable or epidemic malaria - extremely effective for a few months, rapid response
  45. 45Sandfly ovipositionEggs laid in damp sites with organic material - makes control at breeding sites difficult; 4 instars; Immature stages very rarely seen in field
  46. 46Adult feedingBoth sexes feed on sugar sources; Females take blood meal for ovarian development; Pool feeders; Host choice varies by species; Endo- or exo-pahgic; Have stomodeal valve to prevent bloodmeal back-flow; Bloodmeal straight to mid-gut
  47. 47Sandfly dispersalAre weak flyers; 'hopping' flight; low dispersion - few hundred metres; Means Leishmania tends to be focal
  48. 48Sandflys as human vectors2 genera are human vectors - Phlebotomus (Old world) and Lutzomyia (New world); +70 species transmit parasite
  49. 49Leishmania development in SandfliesSandfly egg to adult - 4 weeks; Amastigotes ingested and multiply; Procyclics develop into nectomonads escape PM and attach to mid-gut; Develop into nectomonads that reproduce; Develop haptomonads and metacyclics; Migrate to stomodeal valve
  50. 50Factors effecting sandfly controlZoonosis vs anthroponosis; One or many reservoirs; Resting/breeding sites scattered or concentrated; Endo or exo phagic; Endo or exo philic; Insecticide resistance
  51. 51Vector control of zoonotic leishmaniasis in humansIRS/ITN can be effective if sandflys are endophilic, transmission is domestic, if main reservoir is common around household; Can target the main reservoir - dogs, rodents, cows etc.
  52. 52Deltamethrin-impregnated nets reduce human landing rates of L. longipalpis in Amazon households>50% bites indoors; Most biting occurs when children are under nets; ITNs reduced landing rate by 80%; ITNs killed 98% flies inside houses
  53. 53Effect of insecticide-impregnated dog collars on incidence of zoonotic VL in Iranian childrenReduce the odds of infection by 61% in dogs and 535 in children; Collars could have a role in control and replace dog culling in some places; Effectiveness depends on importance of wild versus domesticated canids
  54. 54Rodent control for Sandfly controlDestroy rodent burrows - potential laying sites for sandflies

Información

Descripción
MSc Medical Parasitology Fichas sobre Vector, creado por tate0295 el 26/04/2015.
Creado por
tate0295 · abr 2015
Actualizado
6 abr 2018
Visitas
12
Valoración

Escríbenos

¿Sobre qué es tu mensaje?

¿Qué te parece el nuevo diseño?

¿Te gusta?