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Chapter 29

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  1. 1kidney stonescalculi
  2. 2clinical manifestations of kidney stonesrenal colic or pain
    usually unilateral
    high reoccurance
  3. 3risk factors of kidney stonesmales
    age 20-40
    inadequate fluid intake
    temperature
    humidity
    fluids
    diet
  4. 4management of kidney stonesstone analysis
    stone removal
  5. 5lower urinary tract obstructionproblems with urine storage or emptying
    neurogenic or anatomic
    overactive bladder syndrome
  6. 6urethral stricturenarrowed urethra
  7. 7pelvic organ prolapsecystocele
  8. 8cystocelebladder prolapses into vagina
  9. 9renal tumorsadenomas - benign
    carcinomas - most common
  10. 10clinical manifestations of renal tumorshematuria
    flank pain
  11. 11bladder tumors1% of all malignant tumors
    hematuria
  12. 12UTIacute or chronic
    inflammation of urinary epithelium
    more common in women
  13. 13acute cystitisinflammation of bladder
  14. 14clinical manifestations of acute cystitislow back or suprapubic pain
    frequency
    dysuria
    urgency
    hematuria
    cloudy urine
  15. 15interstitial cystitisnon-bacterial
    unknown cause
  16. 16clinical manifestations of interstitial cystitisbladder fullness
    frequency
    small urine volume
    chronic pelvic pain
  17. 17acute polyonephritisupper urinary tract infection
    ureter, renal pelvis, and or renal paranchyma
  18. 18clinical manifestations of pyelonephritisfever
    chills
    flank pain
    nausea and vomiting
    costovertebral tenderness
    purulent urine
  19. 19glomerulonephritisinflammation of glomerulus
  20. 20acute glomerulonephritisassociated with strep
    antigen/antibody complex form and deposit in glomerulus
    activation of complement
  21. 21hematuriasmoky, brown-tinged urine
  22. 22decreased GFRdecreased glomerular perfusion due to inflammation
    glomerular sclerosis or scarring
    thickening of glomerular basement membrane
  23. 23proteinurialow serum albumin
    edema
  24. 24oliguriaurine output <30ml/hour
  25. 25stages of acute glomerulonephritishematuria
    proteinuria
    eventually oliguria
  26. 26nephrotic syndromeexcretion of plasma proteins in urine
    increased glomerular capillary permeability
  27. 27acute renal failuresudden and rapidly progressive within hours
    often reversible
  28. 28acute renal failure classified aspre renal failure
    intra renal failure
    post renal failure
  29. 29pre renal ARFmost common
    sudden reduction in perfusion to the kidneys
    GFR declines
    results in oliguria
  30. 30intrarenal ARFdamage to the renal parenchyma
    acute tubular necrosis
    vascular disease
    toxic injury
  31. 31post renal ARFrare
    occurs with urinary obstructions that affect both kidneys
    increases intraluminal pressure upstream/decreases GFR
  32. 32clinical manifestations of ARFazotemia
    uremia
    oliguria
    hyperkalemia
    metabilic acidosis
    hypertension
  33. 33uremic frostaccumulation of urea and other nitrogenous waste products
    accumulate in sweat
    form crystals on skin
  34. 34Chronic Kidney Diseaseirreversible loss of renal function
    affects most all organ systems
  35. 35renal failuresignificant loss of function
    increased BUN/creatinine
    oliguria
  36. 36reduced renal reserveGFR reduced to 50%
    no clinical symptoms
    BUN may be elevated
  37. 37renal insufficiencyGFR declines to 25%
    compensation of remaining nephrons
    mild clinical symptoms
    increased BUN/creatinine
    mild anemia
    impaired renal function during stress
  38. 38end-stage renal diseaseGFR < 5
    sever uremia
    severe imbalances
    miltiorgan/multisystem failure
  39. 39cardivascular failurehypertension, heart failure
    atherosclerosis, stroke, CAD
  40. 40neurologic failureneuropathies
    encephalopathy
  41. 41hematologic failureanemia
    platelet defects
  42. 42gastrointestinal failurenausea and vomiting
    anorexia
    uremic
  43. 43metabolic failurealtered protein, lipid, CHO metabolism
  44. 44integumentary/musculoskeletal failurehyperphosphatemia and hypocalcemia
    hyperparathyroidism; brittle bones
    skin changes
  45. 45immune failureimmunosuppression
  46. 46endocrine failureinsulin resistance
    decreased sex hormones

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Alterations of Renal and Urinary Tract Function
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