inflammatory Response

Localized tissue response to injury

Damaged cells and mast cell release histamine which cause capilaries to dilate and become more permeable.

Enlarged capilaries cause skin to redden.

Swelling stimulates free nerve endings,causing pain.

Neutrophils and monocytes migrate to the site of injury.

Acute-phase proteins,released by the liver in response to inflammatory mediators,make it easier for phagocytes to engulf innvaders.