I always feel tired

I always feel tired

1. anemia

   • red cell mass reduction
   • types
     • in relation to size
       • microcytic
         • sidroblastic anemia
           • flaw in heme synthesis
         • chronic diseases of anemia
           • inhibits release of iron from stores
         • iron deficiency
           • most common anemia
           • iron deficiency of anemia treatment
             • iron supplements
               • oral
               • IV
             • best absorped on empty stomach
       • macrocytic
         • magaloblastic anemia
           • deficiency of vit B12 or folate
       • normocytic
         • hemolytic anemia
           • thalassemia
             • minimized globin chain synthesis
           • sickle cell anemia
             • an aberrant hemoglobin is caused by a genetic abnormalities
           • hereditary spherocytosis
             • genetic flaws in the ankyrin and spectrum genes
       • MCV
     • in relation to the pathophysiology
       • blood loss
       • hemolytic
       • minimized production

2. risks of becoming a vegetarian

   • high risk of colorectal cancer
   • lower bone mineral density
   • lower levels of iron and B12

3. hematopoiesis

   • blood cells production
   • erythropoiesis
     • happens in the bone narrrow
     • hemoglobin
       • synthesis
         • globin synthesis
         • heme synthesis
           • iron
             • iron transportation
           • protoporphyrin
       • kinds
         • adult
           • A2 (a2d2)
           • A (a2b2)
         • embryonic
           • (z2e2) Gower 1
           • (z2g2) Portland
           • (a2e2) Gower II
         • fetal
           • a2g2
     • RBC’s Characteristics
       • biconcave
       • disc-shaped
       • anuclear cells
       • 7-8 micrones in diameter
       • internal volume of 80-100 fL
       • live for 120 days

4. history taking

   • family background
   • chronic illness history
   • gynecological as well as gastrointestinal history
   • differences in the body weight
   • bowel movement
   • dieting
   • medicines overdose
   • exposures to the environment
     • lead poising

5. examination

   • blood count completely
     • iron knowledge
       • TIBC
         • amount of iron that is available for use
       • % saturation
         • iron' share of the transferring volume
       • serum iron
         • iron in plasma amount
       • serum ferritin
         • iron in the stores amount
     • RBC incides
       • MCV
       • RDW
       • PCV
   • electrophoresis
     • molecules moved by an electric current.
   • blood feud
     • assessing
       • WBC's morphology
       • platelets morphology
       • RBC's morpholog
         • size
         • shape
           • poikilocytosis
         • color
           • hypochromia
           • hyperchromia
           • polychromia
           • anisochromia

6. an examination of the body

   • inspection
     • arms
       • scratch marks
       • ecchymosis
     • hands
       • kolionchia
     • eyes
       • pallor
       • jaundice
     • mouth
       • angular stomatitis
       • atrophic glossitis

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