ILO's

Página 1

Define the differences between protozoan and metazoan parasites and give examples of each.

Describe appropriate methods of parasite control currently available and explain the difficulties associated with some of these treatments.

Demonstrate a clear knowledge of key nematode infections of animals.

Expain the significance and modes of transmission of the dog ascarid Toxocara canis.

Demonstrate a clear knowledge and understanding of the main Trichostrongylid gastro-intestinal nematode parasites of sheep and cattle.

Detail the lifecycle and epidemiology of Haemonchus contortus in sheep and Ostertagia ostertagi in cattle.

Describe the distinct pathogenesis associated with each species in the respective host.

Be able to identify the gross and microscopic features of key nematode parasites of animals.

•The veterinary significance of Taenia species

•The life cycles of Taenia species

•Identify appropriate life cycle stages

•Understand issues surrounding vaccination

•Describe the life cycle of Echinococcus sp

•Be aware of the zoonotic potential of Echinococcus sp

•Knowledge of control of Echinococcus sp

Describe the type of immune response elicited by helminth parasites

• Explain how immune responses become polarised during helminth infection

Describe the role of Th2 and regulatory T cells in helminth immune responses

• Understand the impact of helminth infections upon other pathogens and allergy/auto-immunity

-Recall transgenic and gene knockout approaches in C. elegans that are used to study gene expression and function.

-Describe the application of C. elegans to the study of nematode protease enzymes.

Describe the different classes of anthelmintic drugs and their modes of action.

Demonstrate an understanding of the development of anthelmintic drug resistance at the molecular level.

Página 2

Describe the rationale behind vaccine development

Understand the basis of vaccine efficacy

Describe the approaches being used to identify suitable parasite proteins

Explain the process involved in testing vaccine candidates

Discuss how new molecular technologies can assist in vaccine development

Detail the potential zoonotic threat from nematodes.

-Describe the diseases caused by these parasites.

-Review the control measures used to prevent infection with these parasites.

Recall protozoan parasites that are of major veterinary significance.

Explain how protozoan parasites can be the cause of significant disease.

Describe diagnostic features of the diseases caused by representative

species of protozoan parasites.

Recall how representative species of protozoan parasites are

transmitted to their hosts.

•Demonstrate a clear knowledge of the main trypanosome and leishmania parasites of dogs, pigs, cattle and man.

•Be able to identify these parasites.

•Detail the lifecycle and epidemiology of these species.

•Describe the distinct pathogenesis associated with each species.

•Describe the nature of the zoonotic threat and control measures.

Discuss why it is beneficial for apicomplexan parasites to manipulate their infected host cells.

Illustrate some of the strategies utilized by apicomplexan parasites to manipulate their host cells.

Describe the mechanisms that Theileria parasites deploy to activate their host cells and direct the outcome of the activation event.

Aim: To describe the different ways in which African trypanosomes can overcome the innate immune system and infect humans.

•List the major trypanosome species affecting man and animals

•Describe the disease syndrome and available chemotherapeutics

•Discuss the co-evolution of various parasite and host factors that have led to an ongoing evolutionary arms race.

•Describe potential applications that arise from studying the arms-race.

Página 3

Describe why T. gondii can be considered to be an important zoonotic agent.

Recall knowledge of the T. gondii life cycle.

Discuss the factors that influence the epidemiology and pathogenesis of zoonotic disease caused by T. gondii.

Describe methods that are used to diagnose and prevent zoonotic toxoplasmosis

Recall the life cycle of Cryptosporidium and how infection is diagnosed.

Discuss the factors that determine the spread of infection from animals to humans and from animal to animal.

Describe the main pathological consequences of infection.

Describe methods used to control disease outbreaks.