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Test

L38 Background T1DM

Usuario eliminado 4 preguntas Actualizado el 26 may 2019

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Preguntas del test (4)

  1. 1Tolerance is a state of immunological unresponsiveness, and an [blank_start]adaptive[blank_end] response of lymphocytes. It exists because lymphocytes have [blank_start]self-reactive[blank_end] receptor, as receptors are formed by somatic recombination and sometimes recognise [blank_start]self-tissue[blank_end]. They must be deleted, or controlled by tolerance.
    1. Aself-reactive
    2. Bself-tissue
    3. Cadaptive
  2. 2Peripheral Tolerance is the mechanism for controlling self reactive cells that escaped deletion in their early stages.
    • 3 ways this may occur:
    1. Ignorance; lymphocytes are [blank_start]physically[blank_end] separated from low conc. self-antigen at “immune privileged sites” eg the [blank_start]brain, eye, testes, foetus[blank_end]. The sites also produce [blank_start]immunosuppressive cytokines[blank_end].
    2. Anergy; antigen specific non-[blank_start]responsiveness[blank_end], a second signal needed from an [blank_start]APC[blank_end] is not there to activate [blank_start]T cell[blank_end].
    3. Suppression; an active process [blank_start]mediated[blank_end] by a suppressor or regulatory lymphocyte.
    1. Aphysically
    2. Bbrain, eye, testes, foetus
    3. Cimmunosuppressive cytokines
    4. Dresponsiveness
    5. EAPC
    6. FT cell
    7. Gmediated
  3. 3Autoimmunity is the breakdown of self tolerance.
    1. AVerdadero
    2. BFalso
  4. 4Diabetes is a T-cell mediated autoimmune disease.
    1. AVerdadero
    2. BFalso

Información

Descripción
El usuario ha eliminado su información de asignaturas Test sobre L38 Background T1DM, creado por Usuario eliminado el 26/05/2019.
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Usuario eliminado
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English
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Creado el 26 may 2019 · actualizado el 26 may 2019
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