Test
Pharmacology XIV
Este test tiene tiempo límite, así que se abre en el reproductor de siempre.
Preguntas del test (21)
1The therapeutic effect of the salicylates is explained on the basis of the ability of the drug to
- AA) Activate autonomic reflexes
- BB) Uncouple oxidative phosphorylation
- CC) Inhibit the synthesis of prostaglandins
- DD) Competitively antagonize prostaglandins at the receptor site
2The mechanism of the antipyretic action of salicylates probably results from
- AA) Inhibition of prostaglandin synthesis in the CNS affecting hypothalamic temperature regulation
- BB) Inhibition of bradykinin in the periphery leading to sweating
- CC) Depression of oxidative enzymes leading to decreased heat production
- DD) Suppression of cholinergic mediators in the hypothalamus
- EE) Stimulation of norepinephrine in the hypothalamus
3The antipyretic action of salicylates is explained in part by
- AA) Analgesia leading to sedation
- BB) Increased blood flow through the hypothalamus
- CC) Cutaneous vasodilation leading to increased heat loss
- DD) Depression of oxidative processes leading to decreased heat production
4The locus of action of aspirin’s central antipyretic effect is the
- Aa. Brain stem
- Bb. Hypothalamus
- Cc. Basal ganglia
- Dd. Limbic system
- Ee. Cerebral cortex
5A patient who has been taking large quantities of aspirin might show increased postoperative bleeding because aspirin inhibits
- Aa. Synthesis of thromboxane A2 and prevents platelet aggregation
- Bb. Synthesis of prostacyclin and prevents platelet aggregation
- Cc. Synthesis of prostaglandin and prevents production of blood platelets
- Dd. Thrombin and prevents formation of the fibrin network
- Ee. G.I. absorption of vitamin K and prevents synthesis of blood clotting factors
6Anti-inflammatory agents, such as aspirin, interfere with hemostasis by
- Aa. Activating antithrombin
- Bb. Preventing vasoconstriction
- Cc. Inhibiting thrombin generation
- Dd. Inhibiting platelet aggregation
- Ee. Inhibiting polymerization of fibrin
7Which of the following anti-inflammatory agents does NOT act primarily by inhibiting activity of prostaglandin synthetase?
- Aa. Diflunisal
- Bb. Ibuprofen
- Cc. Triamcinolone
- Dd. Oxyphenbutazone
- Ee. Acetylsalicylic acid
8A nonsteroidal, anti-inflammatory agent that appears to produce fewer gastrointestinal disturbances than high does of aspirin is
- Aa. Ibuprofen
- Bb. Probenecid
- Cc. Pentazocine
- Dd. Acetaminophen
- Ee. Phenylbutazone
9Prolonged use of which of the following drugs does NOT cause a predisposition to gastric irritation and bleeding?
- Aa. Phenytoin
- Bb. Ibuprofen
- Cc. Indomethacin
- Dd. Phenylbutazone
- Ee. Acetylsalicylic acid
10Each of the following agents has been associated with gastric irritation EXCEPT
- Aa. Aspirin
- Bb. Alcohol
- Cc. Ibuprofen
- Dd. Indomethacin
- Ee. Acetaminophen
11Which of the following is NOT produced by excessive doses of acetylsalicylic acid?
- Aa. Delirium
- Bb. Tinnitus
- Cc. Hypothermia
- Dd. Hyperventilation
- Ee. Metabolic acidosis
12All of the following are pharmacologic and toxicologic properties of aspirin EXCEPT
- Aa. Tinnitus
- Bb. Analgesia
- Cc. Salicylism
- Dd. Antipyresis
- Ee. Suppression of the immune response
13Therapeutic effects of aspirin include
a. Analgesia
b. Tranquilization
c. Pyretic action
d. Anti-inflammatory action
e. Antirheumatic action- AA) (a), (b) and (c)
- BB) (a), (c) and (d)
- CC) (a), (d) and (e)
- DD) (b), (c) and (d)
- EE) (b), (d) and (e)
14All of the following are pharmacologic or toxicologic properties of acetylsalicylic acid EXCEPT
- Aa. Tinnitus
- Bb. Analgesia
- Cc. Antipyresis
- Dd. Methemoglobinemia
- Ee. Inhibition of prostaglandin synthesis
15All of the following are possible effects of aspirin EXCEPT
- Aa. Reduction of fever
- Bb. Shortening of bleeding time
- Cc. Suppression of inflammatory response
- Dd. Bleeding from the gastronintestinal tract
- Ee. Increase in the renal excretion of uric acid at high doses
16Of the following, aspirin does NOT cause
- Aa. Occult bleeding
- Bb. Nausea and vomiting
- Cc. Acid-base disturbance
- Dd. Suppression of the cough reflex
- Ee. Decreased tubular reabsorption of uric acid
17Which of the following is NOT true regarding acetaminophen?
- Aa. It has antipyretic properties
- Bb. It may induce methemoglobinemia
- Cc. It can be combined with codeine
- Dd. It has anti-inflammatory properties
- Ee. It is not cross-allergenic with aspirin
18The most prominent acute toxic effect associated with acetaminophen use is
- Aa. Hemorrhage
- Bb. Renal necrosis
- Cc. Hepatic necrosis
- Dd. Gastric ulceration
- Ee. Respiratory alkalosis
19Which of the following anti-inflammatory agents does NOT act primarily by inhibiting the activity of cyclooxygenase?
- Aa. Ibuprofen
- Bb. Diflunisal
- Cc. Prednisone
- Dd. Indomethacin
- Ee. Phenylbutazone
20Which of the following is the most appropriate drug to use to lower fever in a child under 12?
- Aa. Aspirin
- Bb. Ibuprofen
- Cc. Acetaminophen
- Dd. Salicylate
- Ee. Diflunisal
21Which analgesic from the following list has the longest half-life?
- Aa. Acetaminophen
- Bb. Aspirin
- Cc. Diflunisal (Dolobid)
- Dd. Ibuprofen
Información
- Descripción
- Praxis Tests: Pharmacology Test sobre Pharmacology XIV, creado por ACAPUN INSTITUTE el 08/11/2021.
- Autor
- ACAPUN INSTITUTE
- Idioma
- Español
- Visitas
- 366
- Etiquetas
- Valoración
- Aún sin valoraciones Valora este test