Signalling L3+4

1. 1Choose the wrong answers

   1. AFor every activation mechanism there must be an inactivation mechanism
   2. BMany of the switch proteins controlled by phosphatase are themselves protein kinases
   3. Cprotein kinases diphosphorylate the switched on protein
2. 2G-protein-linked receptors are made from a [blank_start]single[blank_end] polypetide that threads back and forth acriss the lipid bilayer [blank_start]7[blank_end] times.

   1. Asingle
   2. B7
3. 3Çhoose the right affirmations about GPCRs:

   1. Athey have 7 transmembrane regions
   2. Bthey couple to heteodimeric G proteins
4. 4Both alpha and BY-subunits are involved in signalling.

   1. AVerdadero
   2. BFalso
5. 5Second messenger that produces cyclic AMP and phosphatase [blank_start]C[blank_end]- [blank_start]adenyl cyclase[blank_end]

   1. AC
   2. Badenyl cyclase
6. 6FIrst messengers are [blank_start]cellular signals[blank_end]

   1. Acellular signals
7. 7CHoose the second messengers from the list:

   1. Acyclic AMP
   2. Badenyl cyclase
   3. CphosphataseC
8. 8[blank_start]a[blank_end] subunits activate adenylyl cyclase. ai subunit inhibits it

   1. Aa
   2. Bbeta
   3. Cgamma
9. 9Cyclic Amp phosphodiesterase doesn't convert Cyclic AMp to normal AMp.

   1. AVerdadero
   2. BFalso
10. 10caffeine inhibits AMP [blank_start]phosphodiesterase[blank_end]

    1. Aphosphodiesterase

11. 11Many effects of cAMP are mediated via [blank_start]PKA[blank_end]

    1. APKA
12. 12[blank_start]Cyclic[blank_end] subunits phosphorylate targets

    1. ACatalytic
    2. BRegulatory
13. 13Adrenaline decreases AMP production

    1. AVerdadero
    2. BFalso
14. 14Adrenaline activates the cAMP through [blank_start]beta adrenergic[blank_end] receptors in the Heart

    1. Abeta adrenergic
15. 15What does DAG stand for? A: [blank_start]diacylglycerol[blank_end]

    1. Adiacylglycerol
16. 16Activation of phospholipase C-B produces [blank_start]IP3[blank_end] and [blank_start]DAG[blank_end]

    1. AIP3
    2. BDAG
17. 17Which kinease phosphorylates serines and threonine?

    1. APKA
    2. Bsmad
    3. CDAG
    4. Dprotein kinease C
18. 18Adrenaline [blank_start]increases[blank_end] cyclic AMP

    1. Aincreases
19. 19Diacylglycerol remains in the plasma membrane and couples with Ca2+ to activate

    1. Asmad
    2. Bpka
    3. Cprotein kinease C
20. 20Unlike GPRs, RTK have oly [blank_start]one[blank_end] transmembrane segment

    1. Aone
21. 21For RTK the signal comes in form of a [blank_start]dimer[blank_end]

    1. Adimer
    2. Btrimer
    3. Cmonomer
22. 22When GTP is bound, Ras is

    1. Aactive
    2. Binactive
23. 23Ras is a dimeric GTPase

    1. AVerdadero
    2. BFalso
24. 24TGF B receptors signal through [blank_start]smad[blank_end] proteins

    1. Asmad
25. 25[blank_start]TGF B[blank_end] receptors are important for mesoderm induction

    1. ATGF B
26. 26GMPcan be produced by soluble [blank_start]guanylyl[blank_end] cyclase

    1. Aguanylyl
27. 27Choose the right answers

    1. ANO is a gas
    2. BNO is not cell-permeable
    3. CNO is short lived
    4. DNO is a local signal
28. 28cGMPcan be produced by [blank_start]guanylyl[blank_end] cyclases

    1. Aguanylyl
    2. BNO
29. 29The substrate for nitric oxide is

    1. Aarginine
    2. Blysine
    3. Cglutamate
    4. Dacetyl choline

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Test sobre Signalling L3+4, creado por mirunaserian el 18/02/2016.

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mirunaserian

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