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MNE First Week Practice Quiz
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Preguntas del test (36)
1Congenital adrenal hyperplasia can be caused by...
- AA lack of 21-Beta-Hydroxylase
- BA lack of 11-alpha-hydroxylase
- CA lack of both
- DA lack of either
- ENone of the above
2A lack of oxytocin can be caused by
- AA problem with the anterior pituitary gland
- BA problem with the supraoptic nucleus of the hypothalamus
- CAn excess of vasopressin
- DGrave's disease
3Oxytocin and vasopressin are protected from degradation by
- AAntigens
- BTheir large size
- CAmidation
- DDisulfide bridges
- EBoth amidation and disulfide bridges
- FAmidation and antigens
4A patient presents with moon facies, abdominal striations, a hump behind the neck, and abdominal adipose tissue build up, tests demonstrate high cortisol and high ACTH levels. This patient most likely has:
- AAddison's disease
- BCushing's Syndrome caused by adrenal malfunction
- CCushing's Syndrome caused by Cushing's disease
- DWollf-Chaikov disease
5Which of these is the strongest inhibitor of ACTH production?
- AHigh cortisol levels
- BSleep-wake transition
- CHigh Growth Hormone levels
- DHyperthyroidism
6A lack of Tyrosine in the thyroid would cause
- AThe overproduction of T4
- BThe underproduction of T3
- CThe overproduction of TBG
- DThe underproduction of both T3 and T4
- EThe underproduction of both TBG and TSH
7Competitive inhibition of the follicular iodide pump due to excess _____________ can halt the production of ___________
- Aperchlorate ; thyroid hormones
- Bthyroid hormones ; TSH
- CTSH ; thyroid hormones
- DOxytocin ; Vasopressin
8(Choose the most accurate answer) - Synthesis of Thyroid hormones (T3 and T4) occurs....
- AIn the pituitary gland
- BIn the thyroid
- CIn the follicular space
- DIn the follicular cells
9A patient in the first trimester of pregnancy presents with hyperthyroidism, high Thyroid hormone levels, and low TSH levels. The recommended course of treatment is
- APTU
- BMethimazole
- CExogenous TSH
- DRadioactive Iodine
10Prenatal iodine deficiency causes
- ACretinism
- BOverproduction of Growth Hormone
- CGrave's disease
- DHashimoto's Thyroiditis
11________ has a longer half-life in plasma
- AT4
- BT3
12Conversion of T4 to T3 occurs in the:
- AThyroid
- BPituitary gland
- CPeripheral tissues
- DTBG
13Choose the correct relationship between somatostatin and the hormone(s) below:
- ASomatostatin inhibits TSH, Promotes GH
- BSomatostatin inhibits both TSH and GH
- CSomatostatin inhibits GH, has no effect on TSH
- DSomatostatin promotes TSH and inhibits GH
- ESomatostatin has no effect on TSH or GH
14Thyroid hormone receptors are:
- ABound to DNA and activated when T3 binds to the receptor
- BIn the nucleus, are activated and bind to DNA when T3 binds the receptor
- COn the membrane of cells, act via second messengers
- DDeactivated by HSP90 binding, which is only removed when T3 binds the receptor
- EOnly activated by T4, not T3
15Hashimoto's thyroiditis is causes
- AHyperthyroidism
- BHypothyroidism
16Cerebral osmoreceptors in the __________ respond to changes in the blood osmolality
- ASupraoptic nucleus
- BOVLT and SFO
- CPosterior pituitary
- DAnterior pituitary
17Plasma concentration of AVP is a function of....
- AADH concentration
- BOsmotic threshold
- COxytocin concentration
- DUrine osmolality and Osmotic Threshold
- EPlasma osmolality and Osmotic Threshold
- FPlasma Osmolality, osmotic threshold, and BP
18Maximum antidiuresis occurs at what concentration of AVP?
- A5 pg/ml
- B20 pg/ml
- C5 mg/ml
19At constant plasma osmolality, a decrease in blood pressure leads to
- AAn increase of AVP concentration
- BAn increase of oxytocin concentration
- CA decrease of AVP concentration
- DBoth A and B
20AVP functions by
- AIncreasing the number of Aquaporins in the kidney tubule lumen
- Bincreasing Protein Kinase A activity in kidney tubule cells
- CExocytosis of AQP2 containing vesicles in kidney tubule cells
- DAll of the above
21Nephrogenic diabetes insipidus is caused by:
- ALack of AVP production in the posterior pituitary
- BProblems with V1a receptors in the CNS
- CProblems with V2 receptors in the kidneys
- DProblems with oxytocin receptors
- EPlacental secretion of vasopressinase
22If excess Potassium is detected, ____________ secretion will occur
- AAldosterone
- BCortisol
- CGrowth Hormone
- DVasopressin
23Steroid receptors work by
- ABinding HSP90 and beginning transcription
- BBinding G-proteins that have been released by membrane receptors
- CReleasing HSP90 upon binding a steroid
24What is the major dimerization partner for receptors?
- ARAR
- BRXR
- CPPAR
- DGR
25In a Stachard plot, a hormone that binds two different receptors with different affinities makes a _________ line.
- AStraight
- BCurved
- CIt actually makes two lines
- DVetical
- EHorizontal
26On a hormone binding curve, a left-shift equals a(n) ___________
- AIncrease in affinity
- BDecrease in affinity
- Cincrease in plasma hormone concentration
- DDecrease in plasma hormone concentration
27In the islet of Langerhans
- ABeta cells produce glucagon
- BGamma cells produce insulin
- CBlood flows from the periphery to the center
- DBeta cells are the most numerous
28In the pancreas, endocrine glands secret ___________ and exocrine glands secrete ___________
- Adirectly into an artery ; directly into a vein
- Binto a vein ; into the digestive system
- Cinto the pancreatic duct ; into the venous system
- Dinto the digestive system ; into the liver
29The cell type(s) of the islet of langerhans that serete Ghrelin are:
- AEpsilon and alpha
- BBeta and alpha
- CF cells
- DBeta only
- Eepsilon only
30Pancreatic F cells release:
- AInsulin
- BGlucagon
- CSomatostatin
- DPancreatic polypeptide
31Put these steps into the proper order for Insulin excretion
1) Rise in ATP
2) Opening of inflowing calcium channels
3) Entry of Glucose through the GLUT2 channel
4)Opening of Voltage gated K channel
5) Insulin secretion- A1, 5, 3, 4, 2
- B3, 1, 5, 2, 4
- C4, 3, 1, 2, 5
- D3, 1, 4, 2, 5
32Insulin exocytosis from Beta cells is most similar to which process:
- ATBG exocytosis from the thyroid follicle cells
- BExocrine gland function of pancreas cells
- CAcetylcholine exocytosis in the Neuromuscular junction
- DPosterior pituitary hormone release
33In the presence of high norepinephrine levels, the exocytosis of insulin from Beta cells is
- AIncreased
- BInhibited
- CUnaffected
- DOnly affected if epinephrine is also present
34How does amylin assist in glycemic regulation
- AIt doesn't
- BSlows gastric emptying
- CBoosts insulin levels
- DForms plaques that speed glucose uptake
35How does caffeine effect Beta cell exhaustion
- ADude, caffeine is bad for you. Everyone knows that.
- BBreaks up amyloid plaques, keeping Beta cells functional longer
- CSlows insulin release, regulating Beta cell function
- DStimulates insulin release, helping relieve type 2 diabetes
- EStimulates insulin release, helping relieve type 1 diabetes
36Over-release of growth hormone in childhood causes:
- AGigantism
- BAcromegaly
- CTSH release
- DGlucocorticoid release
Información
- Descripción
- Practice questions for the first week of MNE
- Autor
- Jim Shimoda
- Idioma
- English
- Visitas
- 188
- Etiquetas
- Valoración
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