Test
REPRO/NEPHRO BLOCK: Week 4 - More Kidneys
Este test tiene tipos de pregunta que se abren en el reproductor de siempre.
Preguntas del test (37)
1What is the correct order of blood vessels in the kidney?
- ARenal artery
Segmental arteries
Lobar arteries
Interlobar arteries
Arcuate arteries
Cortical radiate arteries
Afferent arterioles
Glomerulus - BRenal artery
Segmental arteries
Lobar arteries
Interlobar arteries
Cortical radiate arteries
Arcuate arteries
Afferent arterioles
Glomerulus - CRenal artery
Lobar arteries
Interlobar arteries
Segmental arteries
Cortical radiate arteries
Arcuate arteries
Afferent arterioles
Glomerulus - DRenal artery
Interlobar arteries
Lobar arteries
Arcuate arteries
Cortical radiate arteries
Segmental arteries
Afferent arterioles
Glomerulus
- ARenal artery
2What is the correct order of veins in the kidney?
- AGlomerulus
Efferent arterioles
Cortical radiate veins
Arcuate veins
Interlobar veins
Lobar veins
Segmental veins
Renal vein - BGlomerulus
Efferent arterioles
Arcuate veins
Cortical radiate veins
Interlobar veins
Lobar veins
Segmental veins
Renal vein - CGlomerulus
Efferent arterioles
Segmental veins
Lobar veins
Interlobar veins
Arcuate veins
Cortical radiate veins
Renal vein - DGlomerulus
Efferent arterioles
Cortical radiate veins
Arcuate veins
Lobar veins
Interlobar veins
Segmental veins
Renal vein
- AGlomerulus
3What is the lymphatic drainage of the kidneys?
- APara-aortic/lumbar lymph nodes
- BDeep inguinal lymph nodes
- CSuperficial inguinal lymph nodes
- DGroin lymph nodes
4Describe the process of bicarbonate reabsorption.
1. Bicarbonate is filtered by the glomerulus
---Inside the tubule it associates with [blank_start]H+[blank_end] to form [blank_start]carbonic acid[blank_end]
2. [blank_start]Carbonic anhydrase[blank_end] catalyses the [blank_start]dissociation[blank_end] of carbonic acid into [blank_start]H2O and CO2[blank_end]
---These can then be [blank_start]absorbed[blank_end] into the tubular cells
3. Inside the cell, [blank_start]carbonic anhydrase[blank_end] catalyses the reaction between H2O and CO2 to form [blank_start]carbonic acid[blank_end] again
4. The carbonic acid then [blank_start]dissociates[blank_end] into [blank_start]H+ and bicarbonate[blank_end] again
5. [blank_start]Selective permeability[blank_end] ensures that the ions are transported in the right directions:
---H+ is [blank_start]secreted back into the lumen[blank_end], as H+ channels are only found on the [blank_start]luminal[blank_end] side
---Bicarbonate is [blank_start]absorbed into the capillaries[blank_end], as bicarbonate channels are only found on the [blank_start]basolateral[blank_end] side- AH+
- Bcarbonic acid
- CCarbonic anhydrase
- Ddissociation
- EH2O and CO2
- Fabsorbed
- Gcarbonic anhydrase
- Hcarbonic acid
- Idissociates
- JH+ and bicarbonate
- KSelective permeability
- Lsecreted back into the lumen
- Mluminal
- Nabsorbed into the capillaries
- Obasolateral
5Describe the process of H+ excretion via titration with phosphate.
1. [blank_start]H2O and CO2[blank_end] react to form [blank_start]carbonic acid[blank_end] inside tubular cells, catalysed by [blank_start]carbonic anhydrase[blank_end]
---NOTE: the H2O and CO2 is [blank_start]new[blank_end], i.e. produced inside the cell and not reabsorbed from the filtrate
2. Carbonic acid dissociates to form [blank_start]H+ and a new bicarbonate ion[blank_end]
3. [blank_start]Bicarbonate[blank_end] is absorbed into the capillary from the [blank_start]basolateral[blank_end] side (via selective permeability)
4. [blank_start]H+[blank_end] is secreted back into the [blank_start]lumen[blank_end] (via selective permeability)
5. Some H+ associates with [blank_start]phosphate ions[blank_end] to form [blank_start]H2PO4[blank_end]
---This is then excreted in the urine- AH2O and CO2
- Bcarbonic acid
- Ccarbonic anhydrase
- Dnew
- EH+ and a new bicarbonate ion
- FBicarbonate
- Gbasolateral
- HH+
- Ilumen
- Jphosphate ions
- KH2PO4
6How much H+ is excreted via titration with phosphate per day?
- A40 mmol/day
- B50 mmol/day
- C60 mmol/day
- D70 mmol/day
7Describe the excretion of H+ via titration with ammonia.
1. [blank_start]Ammonia[blank_end] is produced in the [blank_start]PCT[blank_end]:
---[blank_start]Glutamine[blank_end] is reabsorbed from the filtrate
---Inside the tubular cell, [blank_start]glutaminase[blank_end] catalyses the breakdown of glutamine into [blank_start]NH4+ and bicarbonate[blank_end]
---[blank_start]Bicarbonate[blank_end] is reabsorbed into the capillary
---[blank_start]NH4+[blank_end] is secreted into the lumen
---NH4+ is converted to [blank_start]NH3[blank_end]
2. [blank_start]H2O and CO2[blank_end] react to form carbonic acid inside tubular cells, catalysed by [blank_start]carbonic anhydrase[blank_end]
---NOTE: the H2O and CO2 is new, i.e. produced inside the cell and not reabsorbed from the filtrate
3. Carbonic acid dissociates to form [blank_start]H+ and a new bicarbonate ion[blank_end]
4. [blank_start]Bicarbonate[blank_end] is absorbed into the capillary from the [blank_start]basolateral[blank_end] side (via selective permeability)
5. [blank_start]H+[blank_end] is secreted back into the [blank_start]lumen[blank_end] (via selective permeability)
6. Some H+ associates with [blank_start]NH3[blank_end] to form [blank_start]NH4+[blank_end]
7.NH4+ is then excreted in the urine- AAmmonia
- BPCT
- CGlutamine
- Dglutaminase
- ENH4+ and bicarbonate
- FBicarbonate
- GNH4+
- HNH3
- IH2O and CO2
- Jcarbonic anhydrase
- KH+ and a new bicarbonate ion
- LBicarbonate
- Mbasolateral
- NH+
- Olumen
- PNH3
- QNH4+
8How much H+ is excreted per day via titration with ammonia?
- A10-50 mmol/day
- B50-100 mmol/day
- C70-100 mmol/day
- D80-130 mmol/day
9How is the amount of H+ excretion in the urine increased when there are high levels of H+ in the blood?
- AUpregulation of glutaminase, leading to increased H+ excretion via titration with ammonia
- BIncreased phosphate excretion, leading to more phosphate in the tubules and increased H+ excretion via titration with phosphate
- CIncreased bicarbonate production in the tubular cells, leading to increased buffering in the blood to decrease H+ levels
- DDown-regulation of H2O and CO2 transport into tubular cells, leading to increased H+ excretion in carbonic acid
10What is the function of the mesangial cells in the juxtaglomerular apparatus?
- AUnknown
- BUnclear: possibly erythropoietin or smooth muscle-like functions
- CConstriction of the efferent arteriole to maintain GFR
- DVasodilation of the afferent arteriole to maintain GFR
11What is the function of juxtaglomerular cells?
- ASecretion of renin
- BSecretion of adenosine
- CDetection of tubular flow
- DVasodilation of the afferent arteriole to maintain GFR
12What is the function of the macula densa?
- ADetect tubular flow
- BAdenosine secretion
- CRenin secretion
- DVasodilation of the afferent artiole to maintain GFR
13How big are the ureters?
- ALength: 25-30 cm
Diameter: 3-4 mm - BLength: 30-35 cm
Diameter: 4-5 mm - CLength: 20-25 cm
Diameter: 2-3 mm - DLength: 35-40 cm
Diameter: 3-4 mm
- ALength: 25-30 cm
14Where are kidney stones most likely to get stuck?
- AUteropelvic junction
- BCrossing over the common iliac arteries at the pelvic brim
- CWhere ureters enter the bladder
- DMedial aspect of the psoas major muscle
- EPoint at which it enters the retroperitoneum
15Which of the following can cause kidney stones?
- APrimary hyperparathyroidism
- BPrimary hypoparathyroidism
- CHypercalcaemia
- DHypocalcaemia
- EPrimary/secondary hyperoxaluria
- FPrimary/secondary hypooxaluria
- GRenal tubular acidosis
- HHypocitraturia
- IHypercitraturia
16What is the correct order for the proportions of different types of kidney stones, from most common to least common?
- ACalcium containing (calcium phosphate/oxalate)
Magnesium ammonium phosphate (Struvite)
Urate
Cysteine
Mixed - BMixed
Calcium containing (calcium phosphate/oxalate)
Magnesium ammonium phosphate (Struvite)
Urate
Cysteine - CMixed
Magnesium ammonium phosphate (Struvite)
Calcium containing (calcium phosphate/oxalate)
Cysteine
Urate - DMagnesium ammonium phosphate (Struvite)
Calcium containing (calcium phosphate/oxalate)
Mixed
Cysteine
Urate
- ACalcium containing (calcium phosphate/oxalate)
17What is the most common composition of kidney stones?
- ACalcium containing (calcium phosphate/oxalate)
- BUrate
- CCysteine
- DStruvite
- EMixed
18How thick should the kidney cortex be?
- A1-2 cm
- B2-3 cm
- C3-4 cm
- D4-5 cm
19How much of the filtrate is reabsorbed by kidneys?
- A99% (180 L/day)
- B95% (175 L/day)
- C90% (165 L/day)
- D80% (140 L/day)
20Why is osmolality used to measure electrolyte concentrations, not osmolarity?
- AOsmolality is temperature independent
- BOsmolality is easier to calculate
- COsmolality is a more reliable measurement
- DOsmolality is recognised internationally
21How long is the PCT?
- A14mm
- B10mm
- C16mm
- D18mm
- E12mm
22How is sodium reabsorbed in the PCT? NOTE: not the co-transporters, just sodium on its own!
- ANa+/H+ exchanger
- BNa+ channel
- CNa+/HCO3- exchanger
- DNa+/Cl- exchanger
23How long is the DCT?
- A1mm
- B2mm
- C3mm
- D4mm
24What proportion of total reabsorption happens in the DCT?
- A25%
- B5%
- C15%
- D30%
- E10%
25What proportion of total reabsorption happens in the thick ascending loop of Henle?
- A25%
- B20%
- C30%
- D35%
26Describe the action of aldosterone.
1. [blank_start]Aldosterone[blank_end] binds to the intracellular [blank_start]mineralocorticoid receptor[blank_end]
2. Aldosterone-receptor complex binds to [blank_start]nucleus[blank_end] and acts as a transcription factor, causing:
---[blank_start]Stimulation of Na+/K+ ATPase[blank_end]
---[blank_start]Increased expression of K+ channels[blank_end] (therefore more potassium [blank_start]excretion[blank_end])
---[blank_start]Increased expression of Na+ channels[blank_end] (therefore more sodium [blank_start]reabsorption[blank_end])- AAldosterone
- Bmineralocorticoid receptor
- Cnucleus
- DStimulation of Na+/K+ ATPase
- EIncreased expression of K+ channels
- Fexcretion
- GIncreased expression of Na+ channels
- Hreabsorption
27What proportion of creatinine is excreted via tubular secretion?
- A0.5%
- B5%
- C10%
- D20%
28What are the correct values of minimum and maximum urine osmolality?
- AMinimum osmolality: 50 mosm/Kg
Maximum osmolality: 1400 mosm/Kg - BMinimum osmolality: 100 mosm/Kg
Maximum osmolality: 2000 mosm/Kg - CMinimum osmolality: 60 mosm/Kg
Maximum osmolality: 1400 mosm/Kg - DMinimum osmolality: 50 mosm/Kg
Maximum osmolality: 1200 mosm/Kg
- AMinimum osmolality: 50 mosm/Kg
29How much waste is excreted in the urine per day?
- A600 mosmol/day
- B400 mosmol/day
- C800 mosmol/day
- D1000 mosmol/day
30What are the correct values for minimum and maximum daily urine output?
- AMinimum urine output: 0.4 L/day
Maximum urine output: 12 L/day - BMinimum urine output: 0.3 L/day
Maximum urine output: 14L/day - CMinimum urine output: 0.5 L/day
Maximum urine output: 12 L/day - DMinimum urine output: 0.6 L/day
Maximum urine output: 14 L/day
- AMinimum urine output: 0.4 L/day
31What can cause dysfunctional reabsorption in the PCT?
- AFanconi's syndrome
- BAcetzolamide
- CBartter's syndrome
- DGitelman's syndrome
- ELiddle's syndrome
- FLoop diuretics
- GThiazide diuretics
- HK-sparing diuretics
32What can cause defective absorption through NKCC2 channels?
- AFanconi's syndrome
- BAcetazolamide
- CBartter's syndrome
- DLoop diuretics
- EGitelman's syndrome
- FThiazide diuretics
- GLiddle's syndrome
- HK-sparing diuretics
33What can cause dysfunctional absorption through NCC channels?
- AFanconi's syndrome
- BAcetazolamide
- CBartter's syndrome
- DLoop diuretics
- EGitelman's syndrome
- FThiazide diuretics
- GLiddle's syndrome
- HK-sparing diuretics
34What can cause dysfunctional reabsorption through ENaC channels?
- AFanconi's syndrome
- BAcetazolamide
- CBartter's syndrome
- DLoop diuretics
- EGitelman's syndrome
- FThiazide diuretics
- GLiddle's syndrome
- HK-sparing diuretics
35What is the normal (healthy) range of urine output per day?
- A0.8-2 L/day
- B0.5-4 L/day
- C0.4-12 L/day
- D0.6-3 L/day
36What is used for the quantification of protein in urinalysis?
- ASpot urinalysis for protein levels
- BUrinary protein:creatinine ratio
- C24 hour urine collection and urinary protein levels
- DConsecutive spot urinalysis for protein levels
37What are the main causes of acute kidney injury or chronic kidney disease?
1. [blank_start]Ineffective blood supply[blank_end]
2. [blank_start]Glomerular disease[blank_end]
3. [blank_start]Tubulo-interstitial disease[blank_end]
4. [blank_start]Obstructive uropathy[blank_end]- AIneffective blood supply
- BGlomerular disease
- CTubulo-interstitial disease
- DObstructive uropathy
Información
- Descripción
- Kidney function and anatomy
- Autor
- Melissa Denker
- Idioma
- English
- Visitas
- 31
- Historial
- Creado el 5 dic 2015 · actualizado el 14 dic 2016
- Etiquetas
- Valoración
- Aún sin valoraciones Valora este test