Flashcards
Jaundice
Cards in this deck (9)
- 1JaundiceJaundice refers to the yellow discolouration of the sclera and skin that is due to hyperbilirubinaemia (this usually occurs at around bilirubin levels >50 µmol/L).
- 2BilirubinJaundice results from high levels of bilirubin in the blood. Bilirubin is the normal breakdown product from the catabolism of haem and thus is formed from the destruction of red blood cells.
- 33 types of Jaundice1- Pre-Hepatic
2-Hepatocellular
3-Post-Hepatic - 4Pre-HepaticIn pre-hepatic jaundice, there is excessive red cell breakdown which overwhelms the liver’s ability to conjugate bilirubin.
- 5HepatocellularIn hepatocellular jaundice, there is dysfunction of the liver itself. The liver loses the ability to conjugate bilirubin,
- 6Post-HepaticPost-hepatic jaundice refers to obstruction of biliary drainage. The bilirubin that is not excreted will have been conjugated by the liver
- 7Potential Causes for Jaundice1. Pre- Hepatic- Haemolytic anaemia
2. Hepatocellular- Alcoholic liver disease
3. Post-Hepatic- Gallstones - 8Laboratory test1. Liver function tests (LFTs)
2. Coagulation studies (PT can be used as a marker of liver synthesis function)
3. FBC (anaemia, raised MCV, and thrombocytopenia all seen in liver disease) - 9TreatmentFor genetic conditions that don't get better, like sickle cell anaemia, a blood transfusion may be given to replenish red blood cells in the body.
If the bile duct system is blocked, an
operation may be needed to unblock it. During these procedures measures may be taken to help prevent further problems, such as removal of the gallbladder.
If the liver is found to be seriously damaged a liver transplant
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- All about Jaundice
- Created by
- Lucy Richardson · Feb 2018
- Updated
- Feb 25, 2018
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