1284785
Description
Flashcards by aaudreylynnn, updated more than 1 year ago
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Created by aaudreylynnn
over 9 years ago
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| Question | Answer |
| sulfur-containing antibiotics | Lincomycins |
| bacteriostatic / bactericidal - depending on the concentration; binds at 50s; inhibit protein synthesis | Lincomycin |
| structure of Lincomycin HCl | contains a basic function, the pyrrolidine nitrogen |
| side effect of lincomycin | pseudomembranous colitis |
| S/E of clindamycin | pseudomembranous colitis |
| IV or IM when oral administration is not feasible | Clindamycin Phosphate |
| p 315 | read |
| glycopeptide antibiotic S. orientalis | Vancomycin HCl |
| a glycopeptide antibiotic that is a tx for endocarditis by gram positive | Vancomycin HCl |
| a glycopeptide antibiotic that is a tx for endocarditis by gram positive | Vancomycin HCl |
| always IV never IM | Vanco |
| S/E of Vancomycin | Ototoxicity, renal damage, phlebitis (inflammation of veins), rashes |
| a mixture of five closely related glycopeptide antibiotics produced by the actinomycete Actinoplanes teichomyceticus. | Teicoplanin |
| Teicoplanin MOA | IM/IV; once a day; impairs bacterial cell wall synthesis less toxic and nephrotoxicity than vancomycin |
| source of teicoplanin | Actinoplanes teichomyceticus |
| source of bacitracin | B. subtilis |
| it is a complex mixture of polypeptides; bactericidal action is enhanced by zinc; inhibit mucopeptide cell wall synthesis | Bacitracin |
| causes less kidney damage than to others | polymyxin B sulfate |
| source of colistin sulfate | Aerobacillus colistinus |
| forms of colistin (2) sulfate methanesulfonate | sulfate - make an oral paediatric suspension methanesulfonate - make IM injection |
| source of gramicidin brand name | Bacillus brevis Kenacomb |
| components of Tyrothricin | gramicidin and tyrocidin |
| gramicidin - more active component of tyrothricin; ionophone | tyrothricin and gramicidin -> gram positive restricted in local applications use |
| source of chloramphenicol | Streptomyces venezuelae |
| prodrug of chloramphenicol intended for pediatric use. | chloramphenicol palmitate |
| brand name and source of Mupirocin | Bactroban; Pseudomonas fluorescens |
| it is a combination of the streptogramin B quinupristin with the streptogramin A dalfopristin in a 30:70 ratio. brand name | Quinupristin/Dalfopristin (Synercid) treatment of serious infections caused by multidrug-resistant Gram-positive organisms such as vancomycin-resistant E. faecium; 2 cods - bactericidal; MOA - 50s; IV |
| source of Quinupristin/dalfopristin | Streptomyces pristinaspiralis |
| an oxazolidinedione-type antibacterial agent that inhibits bacterial protein synthesis brand name | ZyvoxLinezolid (Zyvox) |
| a first-in-class (a glycylcycline) in- travenous antibiotic | Tigecycline (Tygacil) |
| source of Aztreonam | Chromobacterium violaceum |
| a synthetic 1-beta-methyl carbapenem that is structurally related to beta-lactam antibiotics, particularly the thienamycin group | Ertapenem (Invanz, for injection) |
| orally bioavailable macrolide brandname | Telithromycin (Ketek) |
| source of platensimycin | Streptomyces platensis |
| a new structural class of antibiotics with very po- tent broad-spectrum activity against Gram-positive bacteria. | platensimycin |
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